Novus Biologicals products are now on bio-techne.com

SPTLC1 Antibody

Images

 
Western Blot: SPTLC1 Antibody [NBP2-56477] - Analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.
Immunocytochemistry/ Immunofluorescence: SPTLC1 Antibody [NBP2-56477] - Staining of human cell line U-2 OS shows localization to endoplasmic reticulum. Antibody staining is shown in green.
Independent Antibodies: Analysis using NBP2-56477 (A) shows similar pattern to independent antibody NBP1-81737 (B).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

SPTLC1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: GISGLKVVGESLSPAFHLQLEESTGSREQDVRLLQEIVDQCMNRSIALTQARYLEKEEKCLPPPSIRVVVTVE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SPTLC1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Western Blot 1:100 - 1:250
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
SPTLC1 Recombinant Protein Antigen (NBP2-56477PEP)

Reactivity Notes

Mouse 88%, Rat 86%

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for SPTLC1 Antibody

  • EC 2.3.1.50
  • hereditary sensory neuropathy, type 1
  • HSAN1
  • LBC1
  • LCB 1
  • LCB1
  • LCB1HSAN
  • Long chain base biosynthesis protein 1
  • MGC14645
  • serine C-palmitoyltransferase
  • serine palmitoyltransferase 1
  • serine palmitoyltransferase, long chain base subunit 1
  • Serine-palmitoyl-CoA transferase 1
  • SPT 1
  • SPT1
  • SPT1HSN1
  • SPTI
  • SPTLC1

Background

Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-89200
Species: Hu, Mu
Applications: IHC, IHC-P, Simple Western, WB
NBP1-76573
Species: Hu, Mu
Applications: ELISA, ICC, ICC/IF, IF, WB
NBP2-45889
Species: Hu
Applications: IHC, IHC-Fr, IHC-P, WB
NBP1-81838
Species: Hu, Mu
Applications: IHC, IHC-P, WB
NBP1-88927
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
AF1056
Species: Rt
Applications: IHC, WB
AF2849
Species: Mu, Rt
Applications: WB
H00728695-B01P
Species: Hu
Applications: ICC/IF, IP, WB
AF5724
Species: Hu, Mu, Rt
Applications: ICC, WB
NBP2-93574
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NBP1-43435
Species: Hu, Mu
Applications: Flow, WB
NB100-74503
Species: Mu, Rt
Applications: ICC/IF, WB
MAB6734
Species: Hu
Applications: IHC
MAB1417
Species: Bv, Hu, Mu
Applications: CyTOF-ready, ICC, IHC, ICFlow
NBP1-87810
Species: Fi, Hu
Applications: ICC/IF, IHC, IHC-P, WB
256-GF
Species: Hu
Applications: BA
AF1157
Species: Mu
Applications: IHC, WB
H00338382-M01
Species: Hu
Applications: ELISA, IP, WB
NBP2-56477
Species: Hu
Applications: WB, ICC/IF

Publications for SPTLC1 Antibody (NBP2-56477) (0)

There are no publications for SPTLC1 Antibody (NBP2-56477).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for SPTLC1 Antibody (NBP2-56477) (0)

There are no reviews for SPTLC1 Antibody (NBP2-56477). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SPTLC1 Antibody (NBP2-56477) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our SPTLC1 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol SPTLC1