Novus Biologicals products are now on bio-techne.com

SPG3A Antibody

Images

 
Immunohistochemistry-Paraffin: SPG3A Antibody [NBP1-90234] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry: SPG3A Antibody [NBP1-90234] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.
Immunohistochemistry-Paraffin: SPG3A Antibody [NBP1-90234] - Staining of human cerebral cortex shows high expression.
Orthogonal Strategies: Immunohistochemistry-Paraffin: SPG3A Antibody [NBP1-90234] - Staining in human cerebral cortex and skeletal muscle tissues using anti-ATL1 antibody. Corresponding ATL1 RNA-seq data are ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

SPG3A Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: IPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESE
Predicted Species
Rat (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATL1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SPG3A Protein (NBP1-90234PEP)
Publications
Read Publication using
NBP1-90234 in the following applications:

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 28726976).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SPG3A Antibody

  • AD-FSP
  • ATL1
  • atlastin GTPase 1
  • atlastin1
  • atlastin-1
  • Brain-specific GTP-binding protein
  • EC 3.6.5.-
  • FSP1
  • GBP3
  • GBP-3
  • GTP-binding protein 3
  • Guanine nucleotide-binding protein 3
  • guanylate-binding protein 3
  • hGBP3
  • Spastic paraplegia 3 protein A
  • spastic paraplegia 3A (autosomal dominant)
  • SPG3
  • SPG3A
  • SPG3AhGBP3

Background

SPG3A is encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

H00006683-M02
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
H00006275-M01
Species: Hu, Mu
Applications: ELISA, ICC/IF, IHC, WB
NBP1-83976
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP3-25538
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
NBP3-14647
Species: Hu
Applications: IHC-P, IP, WB
AF748
Species: Hu, Mu
Applications: CyTOF-ready, Dual ISH-IHC, Flow, ICC, IHC, Simple Western, WB
NB300-223
Species: Bv, Ca, Ch, Eq, Hu, Mu, Po, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, WB
NBP1-77397
Species: Hu, Mu
Applications: Flow, IB, ICC/IF, IHC, IHC-P, KD, Simple Western, WB
NBP1-76816
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, WB
NBP1-93476
Species: Hu
Applications: IHC, IHC-P
NBP2-01860
Species: Ca, Hu, Pm, Mu, Rt
Applications: Flow, ICC/IF, IHC, WB
NBP1-59662
Species: Hu
Applications: IHC, IHC-P, WB
DMP900
Species: Hu
Applications: ELISA
NBP2-03972
Species: Hu, Mu
Applications: IHC, IHC-P, WB
NBP2-20471
Species: Hu
Applications: IHC, IHC-P, WB
NBP1-91258
Species: Bv, Ca, Eq, Fe, Hu, Mu, Po, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
NBP1-90234
Species: Hu, Mu, Rt
Applications: IHC

Publications for SPG3A Antibody (NBP1-90234)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-P.


Filter By Application
IHC-P
(1)
All Applications
Filter By Species
Mouse
(1)
All Species

Reviews for SPG3A Antibody (NBP1-90234) (0)

There are no reviews for SPG3A Antibody (NBP1-90234). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for SPG3A Antibody (NBP1-90234) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our SPG3A Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol ATL1