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Somatostatin Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Somatostatin Antibody [NBP1-87022] - Staining in human cerebral cortex and tonsil tissues . Corresponding SST RNA-seq data are presented for the same tissues.
Immunohistochemistry: Somatostatin Antibody [NBP1-87022] - Staining of mouse dentate gyrus shows moderate to strong positivity in a subset of neurons in the polymorph layer.
Immunohistochemistry-Paraffin: Somatostatin Antibody [NBP1-87022] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons, as well as immunoreactivity in neural processes.
Immunohistochemistry-Paraffin: Somatostatin Antibody [NBP1-87022] - Staining of human duodenum shows strong cytoplasmic positivity in neuroendocrine cells.
Immunohistochemistry-Paraffin: Somatostatin Antibody [NBP1-87022] - Staining of human pancreas shows strong cytoplasmic positivity in a subset of cells in islets of Langerhans.
Immunohistochemistry-Paraffin: Somatostatin Antibody [NBP1-87022] - Staining of human tonsil shows no positivity in lymphoid cells as expected.
Immunohistochemistry: Somatostatin Antibody [NBP1-87022] - Staining of mouse brain shows strong positivity in a subset of neurons in the cerebral cortex.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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Somatostatin Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: APSDPRLRQFLQKSLAAAAGKQELAKYFLAELLSEPNQTENDALEPEDLSQAAEQDEMRLELQRSANSNPAMAPRERKAGCKN
Predicted Species
Rat (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SST
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Somatostatin Protein (NBP1-87022PEP)
Publications
Read Publication using NBP1-87022.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Somatostatin Antibody

  • Growth hormone release-inhibiting factor
  • SMST
  • SOM
  • Somatostatin
  • somatostatin-14
  • somatostatin-28
  • SRIF
  • SST

Background

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Somatostatin Antibody (NBP1-87022)(1)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for Somatostatin Antibody (NBP1-87022)

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Blogs on Somatostatin.

Successful Transplantation of Friedreich Ataxia Induced Pluripotent Stem Cell (iPSC)-Derived Sensory Neurons in Dorsal Root Ganglia of Adult Rodents
Jamshed Arslan, Pharm D, PhD The dorsal root ganglia (DRG) are a collection of cell bodies of sensory nerves carrying sensory information – including nociception, mechanoreception and proprioception – from periphera...  Read full blog post.

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Bioinformatics

Gene Symbol SST