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Somatostatin R2/SSTR2 Antibody

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Immunocytochemistry/ Immunofluorescence: Somatostatin R2/SSTR2 Antibody [NB300-157] - U2OS cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X PBS + 0.05% Triton X-100. The ...read more
Immunohistochemistry-Paraffin: Somatostatin R2/SSTR2 Antibody [NB300-157] - Staining of Somatostatin Receptor 2 in mouse pancreas using DAB with hematoxylin counterstain.
Immunohistochemistry-Paraffin: Somatostatin R2/SSTR2 Antibody [NB300-157] - Staining of paraffin embedded rat pancreas tissue.

Product Details

Summary
Reactivity Hu, Mu, Rt, PoSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IP, MS
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Somatostatin R2/SSTR2 Antibody Summary

Immunogen
A synthetic peptide made to the C-terminus of rat Somatostatin Receptor 2 [UniProt# P30680]
Localization
Cell Membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SSTR2
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Electron Microscopy
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence 1:100 - 1:250
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Frozen 1:100
  • Immunohistochemistry-Paraffin 1:100
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:100 - 1:1000
Control Peptide
Somatostatin R2/SSTR2 Peptide (NB300-157PEP)
Publications
Read Publications using
NB300-157 in the following applications:

Reactivity Notes

Porcine reactivity reported in scientific literature (PMID:33002813)

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.05% Sodium Azide
Purity
Unpurified

Notes

Licensed to Novus Biologicals LLC under U.S. Patent No 5,998,154.

Alternate Names for Somatostatin R2/SSTR2 Antibody

  • Smstr2
  • Somatostatin R2
  • somatostatin receptor 2
  • somatostatin receptor type 2
  • SomatostatinR2
  • SRIF-1
  • SS2R
  • SS-2-R
  • SS2-R
  • SST2
  • SSTR2

Background

Somatostatin is a tetradecapeptide that is widely distributed in the body. It acts on multiple organs in the body and also functions as a neuropeptide affecting electrical activity of neurons. Somatostatin Receptor 2 (SSR2), along with SSR1, is expressed at the highest levels in the stomach and jejunum, cerebrum and kidney, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Somatostatin R2/SSTR2 Antibody (NB300-157)(10)

We have publications tested in 3 confirmed species: Human, Rat, Porcine.

We have publications tested in 6 applications: FLOW, ICC/IF, IF/IHC, IHC-Fr, IHC-P, WB.


Filter By Application
FLOW
(2)
ICC/IF
(1)
IF/IHC
(2)
IHC-Fr
(2)
IHC-P
(2)
WB
(5)
All Applications
Filter By Species
Human
(4)
Rat
(2)
Porcine
(1)
All Species
Showing Publications 1 - 10 of 10.
Publications using NB300-157 Applications Species
Mandriani B, Pellè E, Mannavola F et al. Development of anti-somatostatin receptors CAR T cells for treatment of neuroendocrine tumors Journal for immunotherapy of cancer 2022-06-01 [PMID: 35764366] (FLOW) FLOW
Yamashita S, Morine Y, Imura S et al. A new pathological classification of intrahepatic cholangiocarcinoma according to protein expression of SSTR2 and Bcl2 World journal of surgical oncology 2021-05-07 [PMID: 33962620] (IF/IHC, Human) IF/IHC Human
Dearling JLJ, van Dam EM, Harris MJ, Packard AB Detection and therapy of neuroblastoma minimal residual disease using [64/67Cu]Cu-SARTATE in a preclinical model of hepatic metastases EJNMMI research 2021-02-25 [PMID: 33630166] (IF/IHC, Human) IF/IHC Human
Jana B, Calka J, Czajkowska M The role of somatostatin and its receptors (sstr2, sstr5) in the contractility of gilt inflamed uterus Research in veterinary science 2020-09-19 [PMID: 33002813] (WB, Porcine) WB Porcine
Wang Z, Ma W, Wang J et al. Imaging and therapy of hSSTR2-transfected tumors using radiolabeled somatostatin analogs. Tumour Biol 2013-04-19 [PMID: 23605323] (FLOW) FLOW
Li F, Ryu BY, Krueger RL et al. Targeted entry via somatostatin receptors using a novel modified retrovirus glycoprotein that delivers genes at levels comparable to wild type viral glycoproteins. Journal of Virology. 2011-10-19 [PMID: 22013043]
Reubi JC, Laissue JA, Waser B et al. Immunohistochemical detection of somatostatin sst2a receptors in the lymphatic, smooth muscular, and peripheral nervous systems of the human gastrointestinal tract: facts and artifacts. J Clin Endocrinol Metab;84(8):2942-50. 1999-08-01 [PMID: 10443702] (IHC-Fr, IHC-P, WB, Human) IHC-Fr, IHC-P, WB Human
Reubi JC, Kappeler A, Waser B et al. Immunohistochemical localization of somatostatin receptors sst2A in human tumors. Am J Pathol;153(1):233-45. 1998-07-01 [PMID: 9665484] (WB, IHC-Fr, IHC-P, Human) WB, IHC-Fr, IHC-P Human
Gu YZ, Schonbrunn A. Coupling specificity between somatostatin receptor sst2A and G proteins: isolation of the receptor-G protein complex with a receptor antibody. Mol Endocrinol;11(5):527-37. 1997-05-01 [PMID: 9139797] (WB, Rat) WB Rat
Dournaud P, Gu YZ, Schonbrunn A et al. Localization of the somatostatin receptor SST2A in rat brain using a specific anti-peptide antibody. J Neurosci;16(14):4468-78. 1996-07-15 [PMID: 8699257] (WB, ICC/IF, Rat) WB, ICC/IF Rat

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Product General Protocols

View specific protocols for Somatostatin R2/SSTR2 Antibody (NB300-157): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Somatostatin R2/SSTR2 Antibody (NB300-157). (Showing 1 - 1 of 1 FAQs).

  1. Is there any data to show that this antibody specifically detects sstr2 since it says that it is unpurified sera?
    • All of our current data for NB300-157 is available online. We have 6 available publications for this antibody as well. This product has been shown to specifically target the protein of interest by WB in published data. If you are interested in a blocking peptide to assist in your research, we do offer one specifically for this antibody - Somatostatin R2 SSTR2 Peptide (NB300-157PEP).

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SSTR2
Entrez
Uniprot