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SMPD1 Antibody (OTI3H7) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
OTI3H7
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-74240AF350
Alexa Fluor 405
NBP2-74240AF405
Alexa Fluor 488
NBP2-74240AF488
Alexa Fluor 532
NBP2-74240AF532
Alexa Fluor 594
NBP2-74240AF594
Alexa Fluor 647
NBP2-74240AF647
Alexa Fluor 700
NBP2-74240AF700
Alexa Fluor 750
NBP2-74240AF750
Biotin
NBP2-74240B
CoraFluor 1
NBP2-74240CL1
DyLight 350
NBP2-74240UV
DyLight 405
NBP2-74240V
DyLight 488
NBP2-74240G
DyLight 550
NBP2-74240R
DyLight 594
NBP2-74240DL594
DyLight 650
NBP2-74240C
DyLight 680
NBP2-74240FR
DyLight 755
NBP2-74240IR
FITC
NBP2-74240F
HRP
NBP2-74240H
Janelia Fluor 549
NBP2-74240JF549
Janelia Fluor 646
NBP2-74240JF646
Janelia Fluor 669
NBP2-74240JF669
Unconjugated
NBP2-45889
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-45889
Azide and BSA Free
NBP2-74240
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SMPD1 Antibody (OTI3H7) [Janelia Fluor® 525] Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 62-341 of human SMPD1 (NP_000534) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SMPD1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SMPD1 Antibody (OTI3H7) [Janelia Fluor® 525]

  • Acid sphingomyelinase
  • aSMase
  • ASMsphingomyelin phosphodiesterase
  • EC 3.1.4.12
  • NPD
  • SMPD1
  • sphingomyelin phosphodiesterase 1, acid lysosomal

Background

The protein encoded by the SMPD1 gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Three transcript variants encoding two different isoforms have been found for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SMPD1