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SLAM/CD150 Antibody (123317)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
123317
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price
Carrier Free
MAB164-SP
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SLAM/CD150 Antibody (123317) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human SLAM/CD150
Ala21-Pro237 (predicted)
Accession # Q13291
Specificity
Detects human SLAM/CD150 in direct ELISA and Western blots. In direct ELISAs, no cross-reactivity with recombinant human 2B4 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
SLAMF1
Purity Statement
Protein A or G purified from ascites
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Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SLAM/CD150 Antibody (123317)

  • CD 150
  • CD150
  • CD150IPO-3
  • CDw150
  • IPO-3
  • signaling lymphocytic activation molecule family member 1
  • signaling lymphocytic activation molecule
  • SLAM
  • SLAMCD150 antigen
  • SLAMF1

Background

Signaling lymphocytic activation molecule (SLAM, SLAMF1; CD150) was the first identified of a family of type I transmembrane (TM) lymphocyte activating receptors. SLAM homotypic adhesion bidirectionally stimulates T and B cells. SLAM is also expressed by hematopoietic stem cells, dendritic cells and platelets and is a T cell measles virus receptor. The 70 kDa glycoprotein contains a 216 amino acid (aa) extracellular domain (ECD) with one C2 type and one V type Ig-like domain, a 20 aa TM sequence and a 76 aa SH2-binding cytoplasmic domain. One splice variant has a shorter cytoplasmic tail and another lacks the TM sequence and is secreted. Human and mouse SLAM ECD share 60% aa identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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SLAM/CD150
Antibody (123317)
MAB164
SLAM/CD150 Antibody (123317)
Species: Hu
Applications: WB

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Bioinformatics

Gene Symbol SLAMF1
Uniprot