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SIT1 Antibody (SIT-01) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IP, CyTOF-ready
Clone
SIT-01
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

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SIT1 Antibody (SIT-01) [DyLight 550] Summary

Immunogen
Bacterially produced recombinant intracellular fragment of human SIT.
Specificity
The antibody SIT-01 reacts with SHP2-interacting transmembrane adaptor protein (SIT) expressed exclusively in lymphoid organs.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SIT1
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow (Intracellular)
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Weak cross-reactivity with mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SIT1 Antibody (SIT-01) [DyLight 550]

  • gp30/40
  • MGC125908
  • MGC125909
  • RP11-331F9.5
  • SHP2 interacting transmembrane adaptor
  • SHP2-interacting transmembrane adapter protein
  • SHP2-interacting transmembrane adaptor protein
  • signaling threshold regulating transmembrane adaptor 1
  • signaling threshold-regulating transmembrane adapter 1
  • SIT1
  • SITMGC125910
  • suppression inducing transmembrane adaptor 1
  • Suppression-inducing transmembrane adapter 1

Background

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Research Areas for SIT1 Antibody (NB500-486R)

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Bioinformatics

Gene Symbol SIT1