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Signal Peptide Peptidase Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-32276AF350
Alexa Fluor 405
NBP2-32276AF405
Alexa Fluor 488
NBP2-32276AF488
Alexa Fluor 532
NBP2-32276AF532
Alexa Fluor 594
NBP2-32276AF594
Alexa Fluor 647
NBP2-32276AF647
Alexa Fluor 700
NBP2-32276AF700
Alexa Fluor 750
NBP2-32276AF750
Biotin
NBP2-32276B
DyLight 350
NBP2-32276UV
DyLight 405
NBP2-32276V
DyLight 488
NBP2-32276G
DyLight 550
NBP2-32276R
DyLight 594
NBP2-32276DL594
DyLight 650
NBP2-32276C
DyLight 680
NBP2-32276FR
DyLight 755
NBP2-32276IR
FITC
NBP2-32276F
HRP
NBP2-32276H
Janelia Fluor 525
NBP2-32276JF525
Janelia Fluor 549
NBP2-32276JF549
Janelia Fluor 585
NBP2-32276JF585
Janelia Fluor 635
NBP2-32276JF635
Janelia Fluor 646
NBP2-32276JF646
Janelia Fluor 669
NBP2-32276JF669
Unconjugated
NBP2-32276
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Signal Peptide Peptidase Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
The immunogen this antibody was made to, maps to a region between residue 327 to 377 of human Signal Peptide Peptidase Like 1 using the numbering given in entry NP_110416.1 (GeneID 81502).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HM13
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Signal Peptide Peptidase Antibody [CoraFluor™ 1]

  • dJ324O17.1
  • EC 3.4.23.-
  • H13hIMP1
  • histocompatibility (minor) 13
  • IMP-1
  • IMP1MSTP086
  • Intramembrane protease 1
  • minor histocompatibility antigen 13
  • minor histocompatibility antigen H13
  • Presenilin-like protein 3
  • PSENL3
  • PSL3IMPAS
  • signal peptide peptidase beta
  • Signal peptide peptidase
  • SPPIMPAS-1

Background

Signal Peptide Peptidase is encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HM13