Home » Serum Response Factor SRF » Serum Response Factor SRF Antibodies » Serum Response Factor SRF Antibody (PCRP-SRF-1F7) [Janelia Fluor® 585]

Serum Response Factor SRF Antibody (PCRP-SRF-1F7) [Janelia Fluor® 585]

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Summary
Product Discontinued
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    • Catalog Number
      NBP3-14188JF585
    • Availability
      Product Discontinued

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Serum Response Factor SRF Antibody (PCRP-SRF-1F7) [Janelia Fluor® 585] Summary

Immunogen
Recombinant full-length human Serum Response Factor SRF protein (Uniprot: P11831)
Localization
Nucleus, Nucleoplasm
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
SRF
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Protein Array
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Serum Response Factor SRF Antibody (PCRP-SRF-1F7) [Janelia Fluor® 585]

  • MCM1
  • serum response factor (c-fos serum response element-binding transcriptionfactor)
  • Serum Response Factor SRF
  • serum response factor
  • SRF

Background

Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF is a cardiac-enriched transcription factor that is required for the appearance of beating sarcomeres in the heart. In addition, SRF may also direct the expression of microRNAs that inhibit the expression of cardiac regulatory factors. SRF binding sites are also constitutive promotor elements in many muscle specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk 1 and SRF accessory protein 1 (SAP 1) have DNA binding properties identical to that of p62TCF

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Serum Response
Factor SRF Antibody ( ...
NBP3-14188JF585
Serum Response Factor SRF Antibody (PCRP-SRF-1F7) [Janelia Fluor® 585]
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IP, MA

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Bioinformatics

Gene Symbol SRF