SerpinB2 Antibody [Unconjugated] Summary
Immunogen |
E. coli-derived recombinant human Serpin B2 Glu2-Pro415 (Asn66-Gln98 del) Accession # P05120 |
Specificity |
Detects human Serpin B2 in direct ELISAs and Western blots. In direct ELISAs, less than 3% cross-reactivity with recombinant human (rh) Serpin B6, rhSerpin B8, and rhSerpin B9 is observed. |
Source |
N/A |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
SERPINB2 |
Purity Statement |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Knockout Validated 2 ug/mL
- Simple Western 1:100 dilution
- Western Blot 1:1000 dilution
|
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C, as supplied.
- 1 month, 2 to 8 °C under sterile conditions after opening.
- 6 months, -20 to -70 °C under sterile conditions after opening.
|
Buffer |
Supplied as a solution in PBS containing BSA, Glycerol and Sodium Azide. |
Preservative |
Sodium Azide |
Notes
* Contains <0.1% Sodium Azide, which is not hazardous at this concentration according to GHS classifications. Refer to SDS for additional information and handling instructions.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for SerpinB2 Antibody [Unconjugated]
Background
Serpin B2 is the gene that encodes plasminogen activator inhibitor 2 (PAI-2), a glycoprotein of 415 amino acids in length. The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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