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Serpin A6/Cortisol Binding Globulin Antibody (SAIC-42B-10) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, MS
Clone
SAIC-42B-10
Clonality
Monoclonal
Host
Rabbit
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-20108AF350
Alexa Fluor 405
NBP3-20108AF405
Alexa Fluor 488
NBP3-20108AF488
Alexa Fluor 532
NBP3-20108AF532
Alexa Fluor 594
NBP3-20108AF594
Alexa Fluor 647
NBP3-20108AF647
Alexa Fluor 700
NBP3-20108AF700
Alexa Fluor 750
NBP3-20108AF750
Biotin
NBP3-20108B
CoraFluor 1
NBP3-20108CL1
DyLight 350
NBP3-20108UV
DyLight 405
NBP3-20108V
DyLight 488
NBP3-20108G
DyLight 550
NBP3-20108R
DyLight 594
NBP3-20108DL594
DyLight 650
NBP3-20108C
DyLight 680
NBP3-20108FR
DyLight 755
NBP3-20108IR
FITC
NBP3-20108F
HRP
NBP3-20108H
Janelia Fluor 525
NBP3-20108JF525
Janelia Fluor 646
NBP3-20108JF646
Janelia Fluor 669
NBP3-20108JF669
PerCP
NBP3-20108PCP
Unconjugated
NBP3-20108-0.2mg
mFluor Violet 450 SE
NBP3-20108MFV450
mFluor Violet 500 SE
NBP3-20108MFV500
mFluor Violet 610 SE
NBP3-20108MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-20108-0.2mg
Azide and BSA Free
NBP3-20108-0.2mg
Azide and BSA Free
NBP3-20108-0.025mg
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Serpin A6/Cortisol Binding Globulin Antibody (SAIC-42B-10) [Janelia Fluor® 549] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Peptide "AQLLQGLGFNLTER" derived from the Corticosteroid-binding globulin SERPINA6, conjugated to KLH.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
SERPINA6
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Mass Spectrometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Serpin A6/Cortisol Binding Globulin Antibody (SAIC-42B-10) [Janelia Fluor® 549]

  • antitrypsin), member 6
  • CBG
  • CBGcorticosteroid-binding globulin
  • corticosteroid binding globulin
  • member 6
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
  • Serpin A6
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
  • transcortin

Background

Corticol binding globulin (CBG or transcotin) binds with high affinity to cortisol in plasma. Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SERPINA6