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SAPS3 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: SAPS3 Antibody [NBP2-34048] - Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm, plasma membrane & cytosol.
Orthogonal Strategies: Immunohistochemistry-Paraffin: SAPS3 Antibody [NBP2-34048] - Staining in human parathyroid gland and pancreas tissues using anti-PPP6R3 antibody. Corresponding PPP6R3 RNA-seq data are ...read more
Immunohistochemistry-Paraffin: SAPS3 Antibody [NBP2-34048] - Staining of human prostate shows strong cytoplasmic and nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: SAPS3 Antibody [NBP2-34048] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: SAPS3 Antibody [NBP2-34048] - Staining of human parathyroid gland shows high expression.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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SAPS3 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: DGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEP
Predicted Species
Mouse (95%), Rat (96%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPP6R3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
SAPS3 Protein (NBP2-34048PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SAPS3 Antibody

  • C11orf23SAPLa
  • chromosome 11 open reading frame 23
  • DKFZp781E17107
  • DKFZp781E2374
  • DKFZp781O2362
  • FLJ11058
  • FLJ43065
  • KIAA1558MGC125711
  • PP6R3MGC125712
  • protein phosphatase 6, regulatory subunit 3
  • SAPLSAP190
  • SAPS domain family member 3
  • SAPS3SAPS domain family, member 3
  • serine/threonine-protein phosphatase 6 regulatory subunit 3
  • Sporulation-induced transcript 4-associated protein SAPL

Background

Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 300141) (Stefansson and Brautigan, 2006 [PubMed 16769727]).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for SAPS3 Antibody (NBP2-34048) (0)

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Secondary Antibodies

 

Isotype Controls

Additional SAPS3 Products

Array NBP2-34048

Research Areas for SAPS3 Antibody (NBP2-34048)

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Bioinformatics

Gene Symbol PPP6R3
Uniprot