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RHD Antibody (roledumab)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
roledumab
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

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RHD Antibody (roledumab) Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'roledumab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
RHD / CD240d
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
RHD
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at -20C in powder form. Store at -80C once reconstituted.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for RHD Antibody (roledumab)

  • blood group Rh(D) polypeptide
  • CD240D
  • DIIIc
  • Rh blood group, D antigen
  • RH
  • RH30
  • Rh4
  • RHCED
  • RhDCw
  • RHDel
  • RHDVA(TT)
  • RhII
  • RhK562-II
  • RhPI
  • RHPII
  • RHXIII

Background

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The classification of Rh positive and Rh negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Alternative splicing of the gene results in four transcript variants encoding four different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Research Areas for RHD Antibody (NBP3-27969)

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Bioinformatics

Gene Symbol RHD
Uniprot