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Recombinant Mouse IFN-beta (Mammalian) Protein

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Bioactivity

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Recombinant Mouse IFN-beta (Mammalian) Protein Summary

Additional Information
A New rm IFN-beta is Available! It has lower endotoxin specifications, is made in-house, and is priced competitively!
Accession #
Protein/Peptide Type
Recombinant Proteins
Gene
Ifnb1

Applications/Dilutions

Dilutions
  • Bioactivity
Theoretical MW
19.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage

After receipt, the product should be kept at -70°C or below for retention of full activity. Thaw product vial by incubation in cold tap water until just thawed - the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Buffer

20 mM Sodium Phosphate, pH 6.4; 300 mM NaCl; 5% Glycerol; 0.1% bovine serum albumin (BSA)

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Mouse IFN-beta (Mammalian) Protein

  • Fibroblast interferon
  • IFB
  • IFBIFNB
  • IFF
  • IFNB
  • IFNB1
  • IFNbeta
  • IFN-beta
  • interferon beta
  • interferon, beta 1, fibroblast
  • MGC96956

Background

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

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Recombinant Mouse
IFN-beta (Mammalian) ...
12405-1
Recombinant Mouse IFN-beta (Mammalian) Protein
Species: Mu
Applications: Bioactivity

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Bioinformatics

Gene Symbol Ifnb1
Uniprot