Rat IL-4 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R? and the common ? chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R? and IL-13 R?1. The type II receptor also transduces IL-13 mediated signals.

We have publications tested in 1 confirmed species: Rat.

Showing Publications 1 - 3 of 3.

Publications using DY504	Applications	Species
Farahzadi, R;Fathi, E;Mesbah-Namin, SA;Vietor, I; Granulocyte differentiation of rat bone marrow resident C-kit+ hematopoietic stem cells induced by mesenchymal stem cells could be considered as new option in cell-based therapy Regenerative therapy 2023-06-01 [PMID: 37206538] (Rat)		Rat
MJ Jeong, S Jeon, HS Yu, WS Cho, S Lee, D Kang, Y Kim, YJ Kim, SY Kim Exposure to Nickel Oxide Nanoparticles Induces Acute and Chronic Inflammatory Responses in Rat Lungs and Perturbs the Lung Microbiome International Journal of Environmental Research and Public Health, 2022-01-04;19(1):. 2022-01-04 [PMID: 35010784] (Rat)		Rat
A Jung, SH Kim, JY Yang, J Jeong, JK Lee, JH Oh, JH Lee Effect of Pulmonary Inflammation by Surface Functionalization of Zinc Oxide Nanoparticles Toxics, 2021-12-06;9(12):. 2021-12-06 [PMID: 34941770] (Rat)		Rat

Array DY504

• IL-4 Antibodies
• IL-4 ELISA Kits
• IL-4 Kit
• IL-4 Proteins
• IL-4 Proteins and Enzymes
• IL-4 ELISAs