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RAD18 Antibody (79B1048.1) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
79B1048.1
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

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RAD18 Antibody (79B1048.1) [Biotin] Summary

Immunogen
The antibody was raised against a synthetic peptide corresponding to the amino acids 402-414 of human Rad18.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
RAD18
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for RAD18 Antibody (79B1048.1) [Biotin]

  • EC 6.3.2.-
  • hHR18
  • hRAD18
  • postreplication repair protein hRAD18p
  • Postreplication repair protein RAD18
  • RAD18 homolog (S. cerevisiae)
  • RAD18, S. cerevisiae, homolog
  • RING finger protein 73
  • RNF73E3 ubiquitin-protein ligase RAD18

Background

RAD18 is encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for RAD18 Antibody (NB100-56523B) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RAD18