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Images
Biological Strategies: Western Blot: PTH1R/PTHR1 Antibody (3D1.1) [NBP1-40067] - PTH1R protein expression by immunoblot of e13.5 tissue lysates from wild type and Ramp2-/- placentas. Image collected and cropped ...read more
Biological Strategies: Western Blot: PTH1R/PTHR1 Antibody (3D1.1) [NBP1-40067] - PTH1R protein expression by immunoblot of e13.5 tissue lysates from wild type and Ramp2-/- placentas. Image collected and cropped ...read more
Immunohistochemistry: PTH1R/PTHR1 Antibody (3D1.1) [NBP1-40067] - Immunofluorescence for PTH1R in the labyrinth of wild type and Ramp2-/- placentas. Scale bars, 100 um. Image collected and cropped by CiteAb from the ...read more
Immunohistochemistry-Paraffin: PTH1R/PTHR1 Antibody (3D1.1) [NBP1-40067] - Analysis of anti-PTH1R antibody with human liver at concentration 5 ug/ml.
Immunohistochemistry: PTH1R/PTHR1 Antibody (3D1.1) [NBP1-40067] - Immunofluorescence for PTH1R in the labyrinth of wild type and Ramp2-/- placentas. Scale bars, 100 um. Image collected and cropped by CiteAb from the ...read more
Immunocytochemistry/ Immunofluorescence: PTH1R/PTHR1 Antibody (3D1.1) [NBP1-40067] - Loss of Ramp2 alters mRNA expression of RAMP2-associating GPCRs, including Pthr1.(A) mRNA expression of RAMP2-interacting GPCRs from ...read more
Immunocytochemistry/ Immunofluorescence: PTH1R/PTHR1 Antibody (3D1.1) [NBP1-40067] - Loss of Ramp2 alters mRNA expression of RAMP2-associating GPCRs, including Pthr1.(A) mRNA expression of RAMP2-interacting GPCRs from ...read more
Product Details
Summary
Reactivity
Hu, Mu, Po, Bv, Ca, Eq, Pm, Pm, Rt, Bt, Ch, Ha, Ma-Op, Pm-Or, RbSpecies Glossary
Synthetic peptide corresponding to aa146-169 of human PTH1R/PTHR1 [RRCDRNGSWELVPGHNRTWANYSE]. Species sequence Homology: Mouse & rat (23/24aa).
Epitope
aa146-169 [RRCDRNGSWELVPGHNRTWANYSE]
Specificity
Recognizes human PTH/PTHrP receptor, MW 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor.
Predicted Species
Rat (96%), Hamster (96%), Chicken (92%), Bat (96%), Opossum (92%), Orangutan (100%), Rabbit (96%). Backed by our 100% Guarantee.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PTH1R
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
parathyroid hormone/parathyroid hormone-related protein receptor
PFE
PTH/PTHr receptor
PTH/PTHrP type I receptor
PTH1 receptor
PTH1R
PTHR
PTHR1
PTHRPTHR1parathyroid hormone receptor 1
seven transmembrane helix receptor
Background
PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR. PTHR1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus. ESTs have been isolated from B-cell/lung/testis, brain, breast, fetus, heart, heart/melanocyte/uterus, kidney, liver/spleen, lung, placenta, and testis libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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