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Proteasome 20S alpha 6 Antibody (OTI4C9) [DyLight 594]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Ca, Pm, PmSpecies Glossary
Applications WB, Flow, IHC
Clone
OTI4C9
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

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Proteasome 20S alpha 6 Antibody (OTI4C9) [DyLight 594] Summary

Immunogen
Full length recombinant protein of human Proteasome 20S alpha 6 (NP_002782) produced in E.coli.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PSMA6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Proteasome 20S alpha 6 Antibody (OTI4C9) [DyLight 594]

  • EC 3.4.25.1
  • IOTA
  • Macropain iota chain
  • macropain subunit iota
  • MGC22756
  • MGC2333
  • MGC23846
  • Multicatalytic endopeptidase complex iota chain
  • p27K
  • p27KPROS-27
  • PROS27
  • PROS-27
  • PROS2727 kDa prosomal protein
  • prosomal P27K protein
  • proteasome (prosome, macropain) subunit, alpha type, 6
  • Proteasome 20S alpha 6
  • Proteasome iota chain
  • proteasome subunit alpha type-6
  • proteasome subunit iota
  • PSMA6

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol PSMA6