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Proteasome 20S alpha 6 Antibody (OTI3B8) [DyLight 680]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI3B8
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-73642AF350
Alexa Fluor 405
NBP2-73642AF405
Alexa Fluor 488
NBP2-73642AF488
Alexa Fluor 532
NBP2-73642AF532
Alexa Fluor 594
NBP2-73642AF594
Alexa Fluor 647
NBP2-73642AF647
Alexa Fluor 700
NBP2-73642AF700
Alexa Fluor 750
NBP2-73642AF750
Allophycocyanin
NBP2-73642APC
Biotin
NBP2-73642B
CoraFluor 1
NBP2-73642CL1
DyLight 350
NBP2-73642UV
DyLight 405
NBP2-73642V
DyLight 488
NBP2-73642G
DyLight 550
NBP2-73642R
DyLight 594
NBP2-73642DL594
DyLight 650
NBP2-73642C
DyLight 755
NBP2-73642IR
FITC
NBP2-73642F
HRP
NBP2-73642H
Janelia Fluor 525
NBP2-73642JF525
Janelia Fluor 549
NBP2-73642JF549
Janelia Fluor 585
NBP2-73642JF585
Janelia Fluor 635
NBP2-73642JF635
Janelia Fluor 646
NBP2-73642JF646
Janelia Fluor 669
NBP2-73642JF669
PE
NBP2-73642PE
PerCP
NBP2-73642PCP
Unconjugated
NBP2-45419
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-45419
Azide and BSA Free
NBP2-73642
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Proteasome 20S alpha 6 Antibody (OTI3B8) [DyLight 680] Summary

Immunogen
Full length recombinant protein of human Proteasome 20S alpha 6 (NP_002782) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PSMA6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Proteasome 20S alpha 6 Antibody (OTI3B8) [DyLight 680]

  • EC 3.4.25.1
  • IOTA
  • Macropain iota chain
  • macropain subunit iota
  • MGC22756
  • MGC2333
  • MGC23846
  • Multicatalytic endopeptidase complex iota chain
  • p27K
  • p27KPROS-27
  • PROS27
  • PROS-27
  • PROS2727 kDa prosomal protein
  • prosomal P27K protein
  • proteasome (prosome, macropain) subunit, alpha type, 6
  • Proteasome 20S alpha 6
  • Proteasome iota chain
  • proteasome subunit alpha type-6
  • proteasome subunit iota
  • PSMA6

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Proteasome 20S
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Proteasome 20S alpha 6 Antibody (OTI3B8) [DyLight 680]
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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PSMA6