PPRC1 Antibody

Images

 
Western Blot: PPRC1 Antibody [NBP1-82985] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane ...read more
Immunocytochemistry/ Immunofluorescence: PPRC1 Antibody [NBP1-82985] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: PPRC1 Antibody [NBP1-82985] - Staining of human liver shows no positivity in hepatoyctes as expected.
Immunohistochemistry-Paraffin: PPRC1 Antibody [NBP1-82985] - Staining of human placenta shows strong cytoplasmic and nuclear positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: PPRC1 Antibody [NBP1-82985] - Staining of human lymph node shows strong nuclear positivity in germinal center cells and non-germinal center cells.
Immunohistochemistry-Paraffin: PPRC1 Antibody [NBP1-82985] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

PPRC1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: ASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQ
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPRC1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Western Blot 0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
PPRC1 Protein (NBP1-82985PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PPRC1 Antibody

  • KIAA0595gamma, coactivator-related 1
  • peroxisome proliferator-activated receptor gamma, coactivator-related 1
  • PGC-1 related co-activator
  • PGC-1-related coactivator

Background

The protein encoded by the PPRC1 gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPARGC1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol PPRC1