PNUTS/PPP1R10 Antibody [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 646

PNUTS/PPP1R10 Antibody [Janelia Fluor® 646] Summary

Immunogen
A synthetic peptide, mapping to a region region between residues 350 and 400 of human Phosphatase Nuclear Targeting Subunit (a.k.a. Protein Phosphatase 1, regulatory subunit 10) using the numbering given in TrEMBL entry Q96QC0 (GeneID 5514).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPP1R10
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PNUTS/PPP1R10 Antibody [Janelia Fluor® 646]

  • CAT53
  • FB19PP1-binding protein of 114 kDa
  • MHC class I region proline-rich protein CAT53
  • p99
  • Phosphatase 1 nuclear targeting subunit
  • phosphatase nuclear targeting subunit
  • PNUTS
  • PNUTSPP1R10
  • PPP1R10
  • Protein FB19
  • protein phosphatase 1 regulatory subunit 10
  • protein phosphatase 1, regulatory (inhibitor) subunit 10
  • protein phosphatase 1, regulatory subunit 10
  • serine/threonine-protein phosphatase 1 regulatory subunit 10

Background

Protein phosphatase 1 (PP1) is found in the cell nucleus and has been implicated in several aspects of nuclear function. Phosphatase 1 nuclear targeting subunit (PNUTS) is a novel protein that exhibits a discreet nuclear compartmentalization and is colocalized with chromatin at distinct phases during mitosis. The subcellular localization of PP1 and the activity toward substrates involved in many aspects of cell physiology have previously been shown to be regulated by association with noncatalytic targeting subunits. The properties of PNUTS are consistent with its role as a targeting subunit for the regulation of nuclear PP1 function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PPP1R10