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PLGF Antibody (358905)

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PlGF was detected in immersion fixed paraffin-embedded sections of human placenta using Human PlGF Monoclonal Antibody (Catalog # MAB2642) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS017) and counterstained with hematoxylin (blue). Specific staining was localized to syncytiotrophoblast cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
PlGF was detected in immersion fixed paraffin-embedded sections of human placenta using Human PlGF Monoclonal Antibody (Catalog # MAB2642) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rat HRP-DAB ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
358905
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB2642-SP
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PLGF Antibody (358905) Summary

Immunogen
E.coli-derived recombinant human PLGF
Ala21-Ala149 (predicted)
Accession # P49763
Specificity
Detects human PLGF in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) CTGF, rhLDGF, rhPDGF, rhVEGF-C, rhVEGF-D, rhVEGF-B 186, rhVEGF 206, or recombinant mouse PlGF-2 is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
PGF
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 8-25 ug/mL
Publications
Read Publications using
MAB2642 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PLGF Antibody (358905)

  • D12S1900
  • PGF
  • PGFL
  • placenta growth factor
  • placental growth factor
  • placental growth factor, vascular endothelial growth factor-related protein
  • PlGF
  • PlGF-2
  • PLGFplacental growth factor-like
  • SHGC-10760

Background

Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. As a result of alternative splicing, at least two PlGF mRNAs encoding monomeric PlGF precursors containing 149 and 170 amino acid residues have been described. The expression of PlGF is not widespread but has been detected in human umbilical vein endothelial cells, placenta, choriocarcinoma cell lines, and in renal cell carcinoma associated with angiogenesis. The PlGF proteins bind with high-affinity to VEGF R1/Flt-1 but not to VEGF R2/Flk-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PLGF Antibody (MAB2642)(3)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 4 applications: Flow Cytometry, ICC, IHC, IHC-P.


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Flow Cytometry
(1)
ICC
(1)
IHC
(1)
IHC-P
(1)
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Human
(3)
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FAQs for PLGF Antibody (MAB2642) (0)

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Bioinformatics

Gene Symbol PGF
Uniprot