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PEX1 Antibody

Images

 
Western Blot: PEX1 Antibody [NBP1-80577] - Analysis in human cell line AN3-CA.
Immunocytochemistry/ Immunofluorescence: PEX1 Antibody [NBP1-80577] - Staining of human cell line A-431 shows positivity in vesicles. Antibody staining is shown in green.
Staining of human cell line A-431 shows localization to peroxisomes.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PEX1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SAPSSMTQDLPGVPGKDQLFSQPPVLRTASQEGCQELTQEQRDQLRADISIIKGRYRSQSGEDESMNQPGPIKTRLAISQSHLMTALGHTRPSISEDDWKNFAELYESFQNPKRRKNQSGTMFRPG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PEX1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Western Blot 0.04 - 0.4 ug/ml
Application Notes
WB reported in scientific literature (PMID: 29884772). ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
PEX1 Protein (NBP1-80577PEP)
Publications
Read Publications using NBP1-80577.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (82%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PEX1 Antibody

  • peroxin-1
  • peroxisomal biogenesis factor 1
  • Peroxisome biogenesis disorder protein 1
  • peroxisome biogenesis factor 1
  • Zellweger syndrome 1
  • Zellweger syndrome
  • ZWS
  • ZWS1

Background

PEX1, also known as Peroxisome biogenesis factor 1, is a 1,283 amino acid protein that is 143 kDa, cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. This protein is currently being studied for research on the following disease and disorders: Zellweger syndrome, peroxisomal biogenesis disorder, peroxisome biogenesis disorders, peroxisome biogenesis factor, Infantile Refsum Disease, Zellweger syndrome-1, refsum disease, neonatal adrenoleukodystrophy, adrenoleukodystrophy, peroxisome biogenesis disorders, Zellweger syndrome spectrum, peroxisome biogenesis disorders (pbd), Werdnig-Hoffmann disease, rhizomelic chondrodysplasia punctate, chondrodysplasia punctate, mulibrey nanism, chondrodysplasia, osteoporosis, hepatocellular carcinoma, and lung carcinoma. PEX1protein involvement has been observed with relation to HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, and HIST1H2BI in peroxisome pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PEX1 Antibody (NBP1-80577)(3)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for PEX1 Antibody (NBP1-80577) (0)

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Bioinformatics

Gene Symbol PEX1
Entrez