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Pet1 Antibody (FEV/7311) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
FEV/7311
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

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Pet1 Antibody (FEV/7311) [Janelia Fluor® 585] Summary

Immunogen
Recombinant fragment (around aa1-200) of human Pet1 protein (exact sequence is proprietary)
Localization
Cell junction. Cell membrane. Single-pass type I membrane protein.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
FEV
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Pet1 Antibody (FEV/7311) [Janelia Fluor® 585]

  • FEV (ETS oncogene family)
  • FEV (fifth Ewing variant)
  • Fifth Ewing variant protein
  • HSRNAFEV
  • PC12 ETS domain-containing transcription factor 1
  • PC12 ETS factor 1
  • PET1
  • Pet-1
  • protein FEV

Background

Pet1 belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional Pet1 Products

Array NBP3-23997JF585

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Bioinformatics

Gene Symbol FEV