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Pentraxin 2/SAP Antibody (APCS/3240) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, MA
Clone
APCS/3240
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-79848AF350
Alexa Fluor 405
NBP2-79848AF405
Alexa Fluor 488
NBP2-79848AF488
Alexa Fluor 532
NBP2-79848AF532
Alexa Fluor 594
NBP2-79848AF594
Alexa Fluor 647
NBP2-79848AF647
Alexa Fluor 700
NBP2-79848AF700
Alexa Fluor 750
NBP2-79848AF750
Allophycocyanin
NBP2-79848APC
Biotin
NBP2-79848B
CoraFluor 1
NBP2-79848CL1
DyLight 350
NBP2-79848UV
DyLight 405
NBP2-79848V
DyLight 488
NBP2-79848G
DyLight 550
NBP2-79848R
DyLight 594
NBP2-79848DL594
DyLight 650
NBP2-79848C
DyLight 680
NBP2-79848FR
DyLight 755
NBP2-79848IR
FITC
NBP2-79848F
HRP
NBP2-79848H
Janelia Fluor 525
NBP2-79848JF525
Janelia Fluor 646
NBP2-79848JF646
Janelia Fluor 669
NBP2-79848JF669
PE
NBP2-79848PE
PerCP
NBP2-79848PCP
Unconjugated
NBP2-79714-100ug
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-79714-100ug
Azide and BSA Free
NBP2-79848
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Pentraxin 2/SAP Antibody (APCS/3240) [Janelia Fluor® 549] Summary

Immunogen
Recombinant fragment of human Pentraxin 2/SAP protein (around aa 143-223) (exact sequence is proprietary) (Uniprot: P02743)
Localization
Secreted
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
APCS
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Protein Array
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Pentraxin 2/SAP Antibody (APCS/3240) [Janelia Fluor® 549]

  • 9.5S alpha-1-glycoprotein
  • amyloid P component, serum
  • APCS
  • MGC88159
  • Pentraxin 2
  • PTX2
  • PTX2serum amyloid P-component
  • SAP
  • SAPpentaxin-related
  • Serum Amyloid P component

Background

Serum Amyloid P (SAP) is a non-fibrillar plasma glycoprotein that belongs to the pentraxin family. It is universally found in amyloid deposits and this is probably due to its specific calcium-dependent binding to motifs present on all types of amyloid fibrils. SAP is also found to prevent fibrillar breakdown by enzymes and it is believed that it helps maintains stability of the amyloid deposits (1,2). It has been shown that SAP binds monocytes with high avidity, but does not bind to erythrocytes, NK cells, T lymphocytes or B lymphocytes (3). SAP production can be induced by exposure to IL-1, IL-6 and IFN-beta. The SAP-inducing activity was neutralized by antibodies to each of the recombinant cytokines (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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DAP1 Antibody -
BSA Free
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Immunocytochemistry/ Immunofluorescence DAP1 Antibody - BSA Free
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Aminopeptidase Antibo
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Bioinformatics

Gene Symbol APCS