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PDE1A Antibody

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Western Blot: PDE1A Antibody [H00005136-B01P] - Analysis of PDE1A expression in transfected 293T cell line by PDE1A polyclonal antibody. Lane 1: PDE1A transfected lysate(59.95 KDa). Lane 2: Non-transfected lysate.
Western Blot: PDE1A Antibody [H00005136-B01P] - Analysis of PDE1A expression in transfected 293T cell line by PDE1A polyclonal antibody. Lane 1: PDE1A transfected lysate(59.95 KDa). Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

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PDE1A Antibody Summary

Description
Quality control test: Antibody reactive against mammalian transfected lysate.
Immunogen
PDE1A (NP_005010.2, 1 a.a. - 545 a.a.) full-length human protein. MGSSATEIEELENTTFKYLTGEQTEKMWQRLKGILRCLVKQLERGDVNVVDLKKNIEYAASVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMTKKKPEEKPKFRSIVHAVQAGIFVERMYRKTYHMVGLAYPAAVIVTLKDVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGIDRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLTDSTEKIVIPLIEEASKAETSSYVASSSTTIVGLHIADALRRSNTKGSMSDGSYSPDYSLAAVDLKSFKNNLVDIIQQNKERWKELAAQGESDLHKNSEDLVNAEEKHDETHS
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
PDE1A
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
It has been used for WB and Functional.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PDE1A Antibody

  • 3'-5' cyclic nucleotide phosphodiesterase
  • 61 kDa Cam-PDE
  • calcium/calmodulin-dependent 3'-5'-cyclic nucleotide phosphodiesterase 1A
  • calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase
  • calmodulin-dependent phosphodiesterase
  • Cam-PDE 1A
  • EC 3.1.4
  • EC 3.1.4.17
  • HCAM1
  • hCam-1
  • HSPDE1A
  • MGC26303
  • PDE1A
  • phosphodiesterase 1A, calmodulin-dependent
  • phosphodiesterase-1A

Background

PDE1A, a variant of PDE1, is a Ca2+-calmodulin-stimulated phosphodieterase (PDE) preferentially hydrolyzing cGMP. Cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. In mammals at least 11 different families of PDEs can be discriminated (PDE1-11) based on their kinetic properties and inhibition to various pharmacological agents. Three different PDE1 genes have been identified (PDE1A, B, and C). PDE1A and PDE1B have higher affinity for cGMP than for cAMP, whereas PDE1C has high affinity for both cAMP and cGMP. The PDE1A gene family includes various proteins that differ from each other at amino and carboxy termini of the protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PDE1A
Uniprot