Home » PD-L2/B7-DC/PDCD1LG2 » PD-L2/B7-DC/PDCD1LG2 Antibodies » PD-L2/B7-DC/PDCD1LG2 Antibody (176611) [mFluor Violet 500 SE]
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PD-L2/B7-DC/PDCD1LG2 Antibody (176611) [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
176611
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 500 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Unconjugated
MAB1224-100
mFluor Violet 450 SE
FAB1224MFV450
mFluor Violet 610 SE
FAB1224MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1224-100
Carrier Free
MAB1224-SP
Carrier Free
MAB1224-500
Carrier Free
MAB1224-100
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PD-L2/B7-DC/PDCD1LG2 Antibody (176611) [mFluor Violet 500 SE] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human PD-L2/B7-DC
Leu20-Pro219 (predicted)
Accession # Q9BQ51
Specificity
Detects human PD-L2/B7-DC in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse PD-L2, recombinant human (rh) B7-1, rhB7-2, rhB7-H1, rhB7-H2, or rhB7-H3 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PDCD1LG2
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PD-L2/B7-DC/PDCD1LG2 Antibody (176611) [mFluor Violet 500 SE]

  • B7-DC
  • bA574F11.2
  • Btdc
  • Butyrophilin B7-DC
  • Butyrophilin-like Protein
  • CD273 antigen
  • CD273
  • CD273PD-1 ligand 2
  • MGC142240
  • PD-1-ligand 2
  • PDCD1L2MGC142238
  • PDCD1LG2
  • PDL2
  • PD-L2
  • PDL2B7DC
  • PD-L2PDCD1 ligand 2
  • programmed cell death 1 ligand 2
  • Programmed death ligand 2

Background

B7-DC is also called programmed death ligand 2 (PDL2). It has recently been clustered as CD273. This ligand is a 42 kD member of the immunoglobulin receptor superfamily expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. B7-DC (CD273) has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. B7-DC (CD273) has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PDCD1LG2