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OX40/TNFRSF4 Antibody (BLR042F)

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Western Blot: OX40/TNFRSF4 Antibody (BLR042F) [NBP2-76421] - Detection of human OX40/CD134 by WB of HH, HeLa, MJ, HEK293T, Hep-G2, C5/MJ, Jurkat, and MOLT-4 lysate. Antibody: Rabbit anti-OX40/CD134 recombinant monoclonal [BLR042F] (NBP2-76421). Secondary: HRP-conjugated goat anti-rabbit IgG.
Western Blot: OX40/TNFRSF4 Antibody (BLR042F) [NBP2-76421] - Detection of human OX40/CD134 by WB of HH, HeLa, MJ, HEK293T, Hep-G2, C5/MJ, Jurkat, and MOLT-4 lysate. Antibody: Rabbit anti-OX40/CD134 recombinant ...read more
Immunocytochemistry/ Immunofluorescence: OX40/TNFRSF4 Antibody (BLR042F) [NBP2-76421] - Detection of human OX40/CD134 (red) in FFPE breast carcinoma by IHC-IF. Antibody: Rabbit anti-OX40/CD134 recombinant monoclonal ...read more
Immunohistochemistry-Paraffin: OX40/TNFRSF4 Antibody (BLR042F) [NBP2-76421] - Section of MJ cells. Antibody: Rabbit anti-OX40/CD134 recombinantmonoclonal antibody [BLR042F] used at 1:250. Secondary: HRP-conjugated goat ...read more
Immunohistochemistry-Paraffin: OX40/TNFRSF4 Antibody (BLR042F) [NBP2-76421] - Detection of human OX40/CD134 in FFPE lung carcinoma. . Antibody: Rabbit anti-OX40/CD134 recombinant monoclonal [BLR042F] (NBP2-76421). ...read more
Independent Antibodies: Immunoprecipitation: OX40/TNFRSF4 Antibody (BLR042F) [NBP2-76421] - Detection of human OX40/TNFRSF4 by WB of immunoprecipitates from MJ lysate. Antibodies: Rabbit anti-OX40/TNFRSF4 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IP
Clone
BLR042F
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

        

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OX40/TNFRSF4 Antibody (BLR042F) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Recombinant protein representing the extracellular domain of human OX40/CD134
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
TNFRSF4
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100 - 1:500
  • Immunohistochemistry 1:100 - 1:500
  • Immunohistochemistry-Paraffin 1:100 - 1:500
  • Immunoprecipitation 20 ul/1mg lysate
  • Western Blot 1:1000
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

Storage
Store at 2 - 8 C / 1 year from date of receipt
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Antigen Affinity-purified

Notes

This Product sold under License from Bethyl Laboratories, Inc.

Alternate Names for OX40/TNFRSF4 Antibody (BLR042F)

  • ACT-135
  • ACT35 antigen
  • ACT35ATC35 antigen
  • CD134 antigen
  • CD134
  • Ly-70
  • OX40 cell surface antigen
  • OX40 homologue
  • OX40
  • OX40L receptor
  • OX40lymphoid activation antigene ACT35
  • TAX transcriptionally-activated glycoprotein 1 receptor
  • tax-transcriptionally activated glycoprotein 1 receptor
  • TNFRSF4
  • tumor necrosis factor receptor superfamily member 4
  • tumor necrosis factor receptor superfamily, member 4
  • Txgp1
  • TXGP1L
  • TXGP1LOX40 antigen

Background

OX40/CD134/TNFSF4 is a member of the TNF-receptor superfamily that has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested OX40/CD134 plays a role in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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OX40/TNFRSF4
Antibody (BLR042F)
NBP2-76421
OX40/TNFRSF4 Antibody (BLR042F)
Species: Hu
Applications: WB, ICC/IF, IHC, IP

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Bioinformatics

Gene Symbol TNFRSF4