Olfactory Marker Protein Antibody - Azide and BSA Free Summary
Immunogen
A synthetic peptide from rat Olfactory Marker Protein conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in mouse.
Localization
Cytoplasmic
Specificity
Highly specific for mature olfactory neurons (including axon and terminals).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
OMP
Purity
Ammonium sulfate precipitation
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Human reactivity reported in scientific literature (PMID: 29288083).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Lyophilized from PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Ammonium sulfate precipitation
Reconstitution Instructions
Reconstitute 0.5 mg size in 0.5 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the 0.1 mg size is provided in reconstituted format.
Alternate Names for Olfactory Marker Protein Antibody - Azide and BSA Free
olfactory marker protein
Olfactory neuronal-specific protein
Background
Olfactory marker protein (OMP) is an abundant, 19-kDa, cytosolic protein that is almost exclusively expressed in mature, functioning, olfactory neurons but not in the neural precursor basal cells. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Its tissue-specific expression in the receptor cells together with the results of the mouse knockout studies show that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. FUNCTION: May act as a modulator of the olfactory signal-transduction cascade. SUBUNIT: Interacts with BEX1 and BEX2. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Uniquely associated with mature olfactory receptor neurons. SIMILARITY: Belongs to the olfactory marker protein family.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Product General Protocols
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Novus Knows the Nose: Sniffing Out the Olfactory Pathway The process of smelling, also known as olfaction, involves thousands of olfactory receptors that transmit signals to the brain. Learn more about the olfactory process in the infographic below.Novus Biologicals offers olfactory related research rea... Read full blog post.
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