NRL Antibody [Biotin] Summary
Specificity |
Detects human NRL in Western blots. |
Source |
N/A |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
NRL |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Packaging, Storage & Formulations
Storage |
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Reconstitution Instructions |
Reconstitute at 0.2 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Background
NRL is a 30 kDa nuclear transcription factor that belongs to the Maf subfamily within the bZIP (basic motif-leucine zipper) transcription factor family. It contains an N‑terminal transcriptional activation domain and a C-terminal DNA-binding bZIP domain that is also involved in homo- or heterodimerization. NRL regulates the expression of rod-specific genes and is expressed specifically in rod photoreceptors. NRL is phosphorylated at multiple sites, which likely regulates its activity. The amino acid sequence of human NRL is 92%, 94%, 90% and 90% identical to that of bovine, canine, rat and mouse NRL, respectively.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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