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NRAMP1/SLC11A1 Antibody

Images

 
Immunohistochemistry-Paraffin: NRAMP1/SLC11A1 Antibody [NBP1-87809] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: NRAMP1/SLC11A1 Antibody [NBP1-87809] - Staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.
Immunohistochemistry-Paraffin: NRAMP1/SLC11A1 Antibody [NBP1-87809] - Staining of human duodenum shows moderate memberanous and cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: NRAMP1/SLC11A1 Antibody [NBP1-87809] - Staining of human liver shows no positivity in hepatocytes as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

NRAMP1/SLC11A1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: TSPGPQQAPPRETYLSEKIPIPDTKPGTFSLR
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC11A1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
NRAMP1/SLC11A1 Protein (NBP1-87809PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for NRAMP1/SLC11A1 Antibody

  • natural resistance-associated macrophage protein 1
  • LSH
  • member 1
  • NRAMP 1
  • NRAMP1
  • NRAMP1solute carrier family 11 (sodium/phosphate symporters), member 1
  • NRAMPnatural resistance-associated macrophage protein 1
  • SLC11A1
  • solute carrier family 11 (proton-coupled divalent metal ion transporters)

Background

"This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLC11A1