Novus Biologicals products are now on bio-techne.com

NPRA/NPR1 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: NPRA/NPR1 Antibody [NBP1-90164] - Staining of human cell line U-2 OS shows localization to nucleoli. Antibody staining is shown in green.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

NPRA/NPR1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids:FHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NPR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
Recommended conditions: Fixation/Permeabilization: PFA/Triton X-100
Control Peptide
NPRA/NPR1 Recombinant Protein Antigen (NBP1-90164PEP)

Reactivity Notes

Expected identity based on immunogen sequence: Mouse (86%), Rat (84%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for NPRA/NPR1 Antibody

  • ANPa
  • ANP-A
  • ANPRA
  • ANPR-A
  • ANPRAEC 4.6.1.2
  • atrial natriuretic peptide receptor 1
  • Atrial natriuretic peptide receptor type A
  • atrionatriuretic peptide receptor A
  • GC-A
  • Guanylate cyclase A
  • GUC2A
  • GUCY2A
  • natriuretic peptide A type receptor
  • natriuretic peptide receptor A
  • natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptidereceptor A)
  • NPR1
  • NPRA
  • NPR-A
  • Pndr

Background

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 (PubMed 7982997)). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-14873
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NBP3-12239
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, IP, WB
NBP1-31365
Species: Ch, Hu, Mu, Rb, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NBP2-46201
Species: Hu
Applications: IHC, IHC-P, WB
NBP2-46617
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NBP2-47602
Species: Hu
Applications: ICC/IF, IHC, IHC-P
AF5415
Species: Hu
Applications: ICC, IHC, Simple Western, WB
AF4414
Species: Hu
Applications: IHC, Simple Western, WB
H00005555-P01
Species: Hu
Applications: ELISA, AP, PA, PAGE, WB
PP-H4417-00
Species: Hu
Applications: DirELISA, IP, WB
NBP1-30027
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NBP1-89090
Species: Hu
Applications: IHC, IHC-P
NB300-605
Species: Hu, Mu, Po, Rt
Applications: Flow, IB, ICC/IF, IHC, IHC-Fr, IHC-P, In vitro, WB
NBP1-90164
Species: Hu
Applications: ICC/IF

Publications for NPRA/NPR1 Antibody (NBP1-90164) (0)

There are no publications for NPRA/NPR1 Antibody (NBP1-90164).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for NPRA/NPR1 Antibody (NBP1-90164) (0)

There are no reviews for NPRA/NPR1 Antibody (NBP1-90164). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for NPRA/NPR1 Antibody (NBP1-90164) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional NPRA/NPR1 Products

Research Areas for NPRA/NPR1 Antibody (NBP1-90164)

Find related products by research area.

Blogs on NPRA/NPR1

There are no specific blogs for NPRA/NPR1, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our NPRA/NPR1 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol NPR1