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NPRA/NPR1 Antibody

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Western Blot: NPR-1/Natriuretic Peptide Receptor A Antibody [NBP1-32889] - Whole cell extract (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with NPR-A antibody [C1C3-2] diluted at 1:500. The ...read more
Western Blot: NPR-1/Natriuretic Peptide Receptor A Antibody [NBP1-32889] - Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE; antibody diluted at 1:1000.

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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NPRA/NPR1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human NPRA/NPR1. The exact sequence is proprietary.
Localization
Membrane
Predicted Species
Mouse (97%), Rat (97%), Bovine (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NPR1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
119 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NBP1-32889 in the following applications:

  • WB
    1 publication

Reactivity Notes

Xenopus laevis (84%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris-Glycine (pH7), 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for NPRA/NPR1 Antibody

  • ANPa
  • ANP-A
  • ANPRA
  • ANPR-A
  • ANPRAEC 4.6.1.2
  • atrial natriuretic peptide receptor 1
  • Atrial natriuretic peptide receptor type A
  • atrionatriuretic peptide receptor A
  • GC-A
  • Guanylate cyclase A
  • GUC2A
  • GUCY2A
  • natriuretic peptide A type receptor
  • natriuretic peptide receptor A
  • natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptidereceptor A)
  • NPR1
  • NPRA
  • NPR-A
  • Pndr

Background

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 (PubMed 7982997)). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for NPRA/NPR1 Antibody (NBP1-32889)(1)

We have publications tested in 1 confirmed species: Xenopus.

We have publications tested in 1 application: WB.


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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NPR1