| Reactivity | MuSpecies Glossary |
| Applications | WB |
| Clonality | Polyclonal |
| Host | Goat |
| Conjugate | Unconjugated |
| Concentration | LYOPH |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse NPRA/NPR1 Ser29-Glu469 Accession # P18293 |
| Specificity | Detects mouse NPRA/NPR1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human (rh) NPR1 is observed and 5% cross-reactivity with rhNPR2 is observed. |
| Source | N/A |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Goat |
| Gene | NPR1 |
| Purity Statement | Antigen Affinity-purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
| Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
| Preservative | No Preservative |
| Concentration | LYOPH |
| Reconstitution Instructions | Reconstitute at 0.2 mg/mL in sterile PBS. |
Mouse Natriuretic Peptide Receptor-1 (NPR1), also known as NPRA, ANP-R1 or guanlyl cyclase-A, is a 130 kDa member of the guanylyl cyclase family of proteins. NPR1 is a 1029 amino acid type I transmembrane glycoprotein that contains a 441 amino acid extracellular domain and a 567 amino acid cytoplasmic region. The cytoplasmic region shows a tyrosine kinase and guanylyl cyclase catalytic domain. NPR1 operates as an oligomer and binds both ANP (atrial natriuretic peptide) and BNP (B-type n.p.) ANP binding induces bronchodilation and a reduction in blood pressure. Over the extracellular domain, mouse NPR1 is 97% and 86% identical to rat and human NPR1, respectively.
![NPRA/NPR1 Antibody [Unconjugated]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "NPRA/NPR1 Antibody [Unconjugated]")
Secondary Antibodies |
Isotype Controls |
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
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