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NPM1 Antibody [mFluor Violet 610 SE]

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NPM1 Antibody [mFluor Violet 610 SE] [NB110-61646MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.
NPM1 Antibody [mFluor Violet 610 SE] [NB110-61646MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 610 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-61646AF350
Alexa Fluor 405
NB110-61646AF405
Alexa Fluor 488
NB110-61646AF488
Alexa Fluor 532
NB110-61646AF532
Alexa Fluor 594
NB110-61646AF594
Alexa Fluor 647
NB110-61646AF647
Alexa Fluor 700
NB110-61646AF700
Alexa Fluor 750
NB110-61646AF750
Allophycocyanin
NB110-61646APC
Biotin
NB110-61646B
CoraFluor 1
NB110-61646CL1
DyLight 350
NB110-61646UV
DyLight 405
NB110-61646V
DyLight 488
NB110-61646G
DyLight 550
NB110-61646R
DyLight 594
NB110-61646DL594
DyLight 650
NB110-61646C
DyLight 680
NB110-61646FR
DyLight 755
NB110-61646IR
FITC
NB110-61646F
HRP
NB110-61646H
Janelia Fluor 525
NB110-61646JF525
Janelia Fluor 549
NB110-61646JF549
Janelia Fluor 646
NB110-61646JF646
Janelia Fluor 669
NB110-61646JF669
PE
NB110-61646PE
PerCP
NB110-61646PCP
Unconjugated
NB110-61646
mFluor Violet 450 SE
NB110-61646MFV450
mFluor Violet 500 SE
NB110-61646MFV500
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-61646
BSA Free
NB110-61646
BSA Free
NB110-61646SS
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NPM1 Antibody [mFluor Violet 610 SE] Summary

Immunogen
A synthetic peptide made to a C-terminal region of human mutant Nucleophosmin (within residues 250-294). [Accession# AAW67752]
Localization
Nucleophosmin typically resides in the nucleus. However, in patients with acute myelogenous leukemia (AML) it mutates and localizes to the cytoplasm.
Specificity
This antibody is specific for the mutant form of Nucleophosmin.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NPM1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 30214626).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NPM1 Antibody [mFluor Violet 610 SE]

  • B23
  • MGC104254
  • NPM1
  • NPMnucleophosmin/nucleoplasmin family, member 1
  • Nucleolar phosphoprotein B23
  • Nucleolar protein NO38
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • Nucleophosmin
  • Numatrin

Background

Nucleophosmin (NPM) is a multi-functional protein that is involved in many cellular activities including cell growth, proliferation and transformation. It is frequently overexpressed in solid tumors, and has recently been found to be mutated and aberrantly localized in the cytoplasm of leukaemic blasts in patients with acute myeloid leukemia (AML).

NMP antibodies are useful tools as tumor markers in cancer research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NPM1