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Human Notch-1 ELISA Kit (Colorimetric)

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ELISA: Notch-1 ELISA Kit [Biotin] [KA2219] - Standard curve

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, NULL
Suitable Sample Type
Cell Lysate, Plasma, Serum
Standard Curve Range
79 to 5000 pg/mL
Sensitivity
n/a

Order Details

  • Size / Catalog#QtyPrice
    KA2219
    1 Kit
    $1,029.00
    6-8 Business Days
Shipping $45.00 per order
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Human Notch-1 ELISA Kit (Colorimetric) Summary

Description
Quality control test: Standard curve. NOTCH1 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human NOTCH1.
Standard Curve Range
79 to 5000 pg/mL
Sensitivity
n/a
Assay Type
Sandwich ELISA
Sample Volume
100 uL
Kit Type
ELISA Kit (Colorimetric)
Gene
NOTCH1

Applications/Dilutions

Dilutions
  • ELISA
  • Quantification

Packaging, Storage & Formulations

Storage
Store at 4C.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Human Notch-1 ELISA Kit (Colorimetric)

  • EC 2.1.2.11
  • EC 3.4.21.68
  • hN1
  • Notch (Drosophila) homolog 1 (translocation-associated)
  • notch 1Notch homolog 1, translocation-associated (Drosophila)
  • Notch homolog 1, translocation-associated
  • Notch1
  • Notch-1
  • TAN1
  • TAN1neurogenic locus notch homolog protein 1
  • Translocation-associated notch protein TAN-1

Background

Notch is synthesized in the endoplasmic reticulum as an inactive form which is proteolytically cleaved by a furin-like convertase (S1 cleavage) in the trans-golgi network before it reaches the plasma membrane to yield an active, ligand-accessible form. Cleavage results in a C-terminal fragment N(TM) and a N-terminal fragment N(EC). Following ligand binding, it is cleaved (S2 cleavage) by TNF-alpha converting enzyme (TACE) to yield a membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). This fragment is then cleaved by presenilin-dependent gamma-secretase (S3 cleavage) to release the intracellular domain (NICD) from the membrane which then translocates to the nucleus to activate transcription of downstream genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol NOTCH1