NKG2C/CD159c/KLRC2 Antibody (134591) [DyLight 755]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
134591
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 755

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NKG2C/CD159c/KLRC2 Antibody (134591) [DyLight 755] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human NKG2C/CD159c and CD94
Specificity
Detects human NKG2C/CD159c heterodimer with CD94 in flow cytometry. It does not cross-react with the human NKG2A/CD94 heterodimer or with the human CD94 homodimer.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KLRC2
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-reported
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for NKG2C/CD159c/KLRC2 Antibody (134591) [DyLight 755]

  • CD159 antigen-like family member C
  • CD159c antigen
  • CD159c
  • killer cell lectin-like receptor subfamily C, member 2
  • KLRC2
  • MGC138244
  • NK cell receptor C
  • NKG2-C type II integral membrane protein
  • NKG2C
  • NKG2-C
  • NKG2CNKG2-C-activating NK receptor

Background

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KLRC2