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NKG2A/CD159a/KLRC1 Antibody (131411) [Allophycocyanin]

 (13 Publications)
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Human peripheral blood lymphocytes were stained with Mouse Anti-Human NKG2A/CD159a APC-conjugated Mono-clonal Antibody (Catalog # FAB1059A) and Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody (Catalog # FAB2408P). Quadrant markers were set based on isotype control antibody staining (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human NKG2A/CD159a APC-conjugated Mono-clonal Antibody (Catalog # FAB1059A) and Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody (Catalog # ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
131411
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1059U-100UG
Alexa Fluor 405
FAB1059V-100UG
Alexa Fluor 488
FAB1059G-100UG
Alexa Fluor 532
FAB1059X
Alexa Fluor 594
FAB1059T-100UG
Alexa Fluor 647
FAB1059R-100UG
Alexa Fluor 700
FAB1059N-100
Alexa Fluor 700
FAB1059N-025
Alexa Fluor 750
FAB1059S-100UG
Allophycocyanin
FAB1059A-100
Allophycocyanin/Cy7
FAB1059APCCY7
Biotin
FAB1059B-025
CoraFluor 1
FAB1059CL1
DyLight 350
FAB1059D
DyLight 405
FAB1059E
DyLight 488
FAB1059K
DyLight 550
FAB1059L
DyLight 594
FAB1059M
DyLight 650
FAB1059W
DyLight 680
FAB1059Y
DyLight 755
FAB1059Z
FITC
FAB1059F
HRP
FAB1059H
Janelia Fluor 525
FAB1059JF525
Janelia Fluor 549
FAB1059I
Janelia Fluor 585
FAB1059JF585
Janelia Fluor 635
FAB1059JF635
Janelia Fluor 646
FAB1059J
Janelia Fluor 669
FAB1059JF669
PE/Atto594
FAB1059PEATT594
PE/Cy5.5
FAB1059PECY55
PE/Cy7
FAB1059PECY7
PerCP (Peridinin-chlorophyll Protein Complex)
FAB1059C-025
PerCP (Peridinin-chlorophyll Protein Complex)
FAB1059C-100
Phycoerythrin
FAB1059P-100
Phycoerythrin
FAB1059P-025
Unconjugated
MAB1059-100
mFluor Violet 450 SE
FAB1059MFV450
mFluor Violet 500 SE
FAB1059MFV500
mFluor Violet 610 SE
FAB1059MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1059-100
Carrier Free
FAB1059B-025
Carrier Free
FAB1059R-100UG
Carrier Free
FAB1059S-100UG
Carrier Free
FAB1059T-100UG
Carrier Free
FAB1059U-100UG
Carrier Free
FAB1059V-100UG
Carrier Free
MAB1059-500
Carrier Free
MAB1059-100
Carrier Free
MAB1059-SP
Carrier Free
FAB1059C-025
Carrier Free
FAB1059N-100
Carrier Free
FAB1059N-025
Carrier Free
FAB1059A-100
Carrier Free
FAB1059P-100
Carrier Free
FAB1059P-025
Carrier Free
FAB1059C-100
Carrier Free
FAB1059G-100UG
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NKG2A/CD159a/KLRC1 Antibody (131411) [Allophycocyanin] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human NKG2A and CD94
Specificity
Recognizes the human NKG2A/CD94 heterodimer. It does not recognize the NKG2C/CD94 heterodimer or the CD94 homodimer.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
KLRC1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB1059A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NKG2A/CD159a/KLRC1 Antibody (131411) [Allophycocyanin]

  • CD159 antigen-like family member A
  • CD159a antigen
  • CD159a
  • C-lectin type II protein
  • killer cell lectin-like receptor subfamily C, member 1
  • Klrc1
  • MGC13374
  • natural killer cell lectin
  • natural killer group protein 2
  • NK cell receptor A
  • NKG2
  • NKG2-1/B activating NK receptor
  • NKG2A
  • NKG2-A
  • NKG2-A/B type II integral membrane protein
  • NKG2-A/B-activating NK receptor
  • NKG2-A/NKG2-B type II integral membrane protein
  • NKG2AMGC59791
  • NKG2-B

Background

NKG2A, also known as CD159a, is a type II transmembrane receptor having a single extracellular lectin-like domain and a cytoplasmic ITIM motif. It associates with CD94 and is expressed on NK cells and some activated T cell populations. The NKG2A/CD94 complex delivers an inhibitory signal upon recognition of its ligand, HLA-E.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for NKG2A/CD159a/KLRC1 Antibody (FAB1059A)(13)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: Flow Cytometry, IHC, Neutralization.


Filter By Application
Flow Cytometry
(7)
IHC
(1)
Neutralization
(1)
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Filter By Species
Human
(8)
All Species
Showing Publications 1 - 10 of 13. Show All 13 Publications.
Publications using FAB1059A Applications Species
Jani Huuhtanen, Henna He Kasanen, Katriina Peltola, Tapio Lönnberg, Virpi Glumoff, Oscar Brück et al. Single-cell characterization of anti–LAG-3 and anti–PD-1 combination treatment in patients with melanoma Journal of Clinical Investigation 3/15/2023 [PMID: 36719749]
Rafael Alonso Alonso Fernández, Jessica Encinas Mayoral, Laetitia Pierre-Louis, Yao Yao, Yan Xu, Shidai Mu et al. Improving NK cell function in multiple myeloma with NKTR-255, a novel polymer-conjugated human IL-15 Blood Advances 1/10/2023 [PMID: 35882498]
Daniel R. Calabrese, Emily Aminian, Benat Mallavia, Fengchun Liu, Simon J. Cleary, Oscar A. Aguilar et al. Natural killer cells activated through NKG2D mediate lung ischemia-reperfusion injury Journal of Clinical Investigation 2/1/2021 [PMID: 33290276]
Xueqin Zhu, Xing Qin, Xiaoning Wang, Yingnan Wang, Wei Cao, Jianjun Zhang et al. Oral cancer cell‑derived exosomes modulate natural killer cell activity by regulating the receptors on these cells International Journal of Molecular Medicine 9/24/2020 [PMID: 33125101]
HC Tseng, W Xiong, S Badeti, Y Yang, M Ma, T Liu, CA Ramos, G Dotti, L Fritzky, JG Jiang, Q Yi, J Guarrera, WX Zong, C Liu, D Liu Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma Nat Commun, 2020-09-23;11(1):4810. 2020-09-23 [PMID: 32968061] (Flow Cytometry, IHC, Human) Flow Cytometry, IHC Human
WC Pump, T Kraemer, T Huyton, GT Hò, R Blasczyk, C Bade-Doedi Between Innate and Adaptive Immune Responses: NKG2A, NKG2C, and CD8? T Cell Recognition of HLA-E Restricted Self-Peptides Acquired in the Absence of HLA-Ia Int J Mol Sci, 2019-03-22;20(6):. 2019-03-22 [PMID: 30909402] (Flow Cytometry, Human) Flow Cytometry Human
Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo PLoS Pathog, 2016-08-03;12(8):e1005788. 2016-08-03 [PMID: 27487232] (Flow Cytometry, Human) Flow Cytometry Human
Yan Chen, Bei Chen, Ti Yang, Weiming Xiao, Li Qian, Yanbing Ding et al. Human fused NKG2D–IL-15 protein controls xenografted human gastric cancer through the recruitment and activation of NK cells Cellular & Molecular Immunology 3/1/2017 [PMID: 26364916]
van Meijgaarden K, Haks M, Caccamo N, Dieli F, Ottenhoff T, Joosten S Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset. PLoS Pathog, 2015-03-24;11(3):e1004671. 2015-03-24 [PMID: 25803478] (Flow Cytometry, Human) Flow Cytometry Human
Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbe C, Caillat-Zucman S Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog., 2012-01-12;8(1):e1002486. 2012-01-12 [PMID: 22253598] (Flow Cytometry, Human) Flow Cytometry Human
Show All 13 Publications.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KLRC1