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Neuromedin BR/NMBR Antibody - BSA Free

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Immunohistochemistry-Paraffin: Neuromedin B R/NMBR Antibody [NLS825] - Human lung, carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval dilution 16 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Po, Bt, Bv, Eq, Rb, Rt, Ca, Ha, Pm, PmSpecies Glossary
Applications Flow, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

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Neuromedin BR/NMBR Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human Neuromedin BR/NMBR.
Epitope
3rd cytoplasmic domain
Specificity
Human NMBR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Rat (94%), Hamster (94%), Canine (94%), Primate (100%), Monkey (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NMBR
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 - 10 ug/ml
Application Notes
Use in Flow Cytometry reported in scientific literature (PMID:32807943).
Control
Neuromedin BR/NMBR Overexpression Lysate
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Publications
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NLS825 in the following applications:

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Xenopus (81%).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Neuromedin BR/NMBR Antibody - BSA Free

  • Neuromedin B R
  • neuromedin B receptor
  • Neuromedin BR
  • neuromedin-B receptor
  • Neuromedin-B-preferring bombesin receptor
  • NMBR
  • NMB-R

Background

The neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: IHC, IHC-P, WB
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Bioinformatics

Gene Symbol NMBR
Entrez