Neurokinin B Antibody Blocking Peptide

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 2 applications: B/N, IHC-Fr.

Showing Publications 1 - 3 of 3.

Publications using NB300-201PEP	Applications	Species
Mittelman-Smith MA, Krajewski-Hall SJ, McMullen NT, Rance NE. Neurokinin 3 Receptor-Expressing Neurons in the Median Preoptic Nucleus Modulate Heat-Dissipation Effectors in the Female Rat Endocrinology 2015-03-31 [PMID: 25825817] (IHC-Fr, Rat)	IHC-Fr	Rat
Cholanian M, Krajewski-Hall SJ, Levine RB et al. Electrophysiology of Arcuate Neurokinin B Neurons in Female Tac2-EGFP Transgenic Mice. Endocrinology 2014-04-15 [PMID: 24735328] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Krajewski SJ, Burke MC, Anderson MJ et al. Forebrain projections of arcuate neurokinin B neurons demonstrated by anterograde tract-tracing and monosodium glutamate lesions in the rat. Neuroscience. 2010-03-17 [PMID: 20038444] (B/N)	B/N

Array NB300-201PEP

• Neurokinin B Antibodies
• Neurokinin B ELISA Kit
• Neurokinin B Lysate
• Neurokinin B Proteins