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MSH2 Antibody [DyLight 488]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-621AF350
Alexa Fluor 405
NB100-621AF405
Alexa Fluor 488
NB100-621AF488
Alexa Fluor 532
NB100-621AF532
Alexa Fluor 594
NB100-621AF594
Alexa Fluor 647
NB100-621AF647
Alexa Fluor 700
NB100-621AF700
Alexa Fluor 750
NB100-621AF750
Biotin
NB100-621B
CoraFluor 1
NB100-621CL1
DyLight 350
NB100-621UV
DyLight 405
NB100-621V
DyLight 550
NB100-621R
DyLight 594
NB100-621DL594
DyLight 650
NB100-621C
DyLight 680
NB100-621FR
DyLight 755
NB100-621IR
FITC
NB100-621F
HRP
NB100-621H
Janelia Fluor 525
NB100-621JF525
Janelia Fluor 549
NB100-621JF549
Janelia Fluor 585
NB100-621JF585
Janelia Fluor 635
NB100-621JF635
Janelia Fluor 646
NB100-621JF646
Janelia Fluor 669
NB100-621JF669
Unconjugated
NB100-621
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MSH2 Antibody [DyLight 488] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 875 and the C-terminus (residue 934) of human mutS homolog 2 using the numbering given in Swiss-Prot entry P43246 (GeneID 4436).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MSH2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MSH2 Antibody [DyLight 488]

  • COCA1
  • DNA mismatch repair protein Msh2
  • FCC1
  • hMSH2
  • HNPCC
  • HNPCC1
  • HNPCC1mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)
  • LCFS2
  • MSH2
  • mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • MutS protein homolog 2

Background

MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MSH2