Mouse Serpin E1/PAI-1 DuoSet ELISA, 5 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.

We have publications tested in 2 confirmed species: Mouse, Transgenic Mouse.

Showing Publications 1 - 7 of 7.

Publications using DY3828-05	Applications	Species
Puspitasari, YM;Ministrini, S;Han, J;Karch, C;Prisco, F;Liberale, L;Bengs, S;Akhmedov, A;Montecucco, F;Beer, JH;Lüscher, TF;Bongiovanni, D;Camici, GG; Hutchinson-Gilford progeria syndrome mice display accelerated arterial thrombus formation and increased platelet reactivity Thrombosis research 2024-07-18 [PMID: 39032390] (Transgenic Mouse)		Transgenic Mouse
Brandt, A;Kromm, F;Hernández-Arriaga, A;Martínez Sánchez, I;Bozkir, HÖ;Staltner, R;Baumann, A;Camarinha-Silva, A;Heijtz, RD;Bergheim, I; Cognitive Alterations in Old Mice Are Associated with Intestinal Barrier Dysfunction and Induced Toll-like Receptor 2 and 4 Signaling in Different Brain Regions Cells 2023-08-27 [PMID: 37681885] (Mouse)		Mouse
Li, L;Geng, J;Yu, W;Zhou, F;Zheng, Z;Fu, K;Kong, J;Feng, X; Inhibition of PPAR? by BZ26, a GW9662 derivate, attenuated obesity-related breast cancer progression by inhibiting the reprogramming of mature adipocytes into to cancer associate adipocyte-like cells Frontiers in pharmacology 2023-08-15 [PMID: 37649895] (Mouse)		Mouse
YH Su, YZ Wu, DK Ann, JL Chen, CY Kuo Obesity promotes radioresistance through SERPINE1-mediated aggressiveness and DNA repair of triple-negative breast cancer Cell Death & Disease, 2023-01-21;14(1):53. 2023-01-21 [PMID: 36681663] (Mouse)		Mouse
Y Sun, F Ye, D Li, H Yang, T Xu, X Zhong, Y Lu, H Zhou, J Pan Fibroblast growth factor 2 (FGF2) ameliorates the coagulation abnormalities in sepsis Toxicology and Applied Pharmacology, 2023-01-06;460(0):116364. 2023-01-06 [PMID: 36621722] (Mouse)		Mouse
WF Fang, YM Chen, CY Lin, HL Huang, H Yeh, YT Chang, KT Huang, MC Lin Histone deacetylase 2 (HDAC2) attenuates lipopolysaccharide (LPS)-induced inflammation by regulating PAI-1 expression J Inflamm (Lond), 2018-01-10;15(0):3. 2018-01-10 [PMID: 29344006] (Mouse)		Mouse
G Hoppe, S Yoon, B Gopalan, AR Savage, R Brown, K Case, A Vasanji, ER Chan, RB Silver, JE Sears Comparative systems pharmacology of HIF stabilization in the prevention of retinopathy of prematurity Proc Natl Acad Sci USA, 2016-04-18;0(0):. 2016-04-18 [PMID: 27091985] (Mouse)		Mouse

Array DY3828-05

• Serpin E1/PAI-1 Antibodies
• Serpin E1/PAI-1 Antibody Pair
• Serpin E1/PAI-1 ELISA Kits
• Serpin E1/PAI-1 Lysate
• Serpin E1/PAI-1 Proteins
• Serpin E1/PAI-1 ELISAs
• Serpin E1/PAI-1 Proteins and Enzyme