Mouse/Rat HGF Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

HGF (Hepatocyte Growth Factor, Scatter Factor) induces the proliferation and migration of epithelial cells, hepatocytes, chondrocytes, keratinocytes, melanocytes, endothelial cells, and many tumor cells. During organogenesis and tissue repair, HGF promotes epithelial/endothelial morphogenesis by inducing cell scattering and branching tubulogenesis. It also supports insulin production by pancreatic beta cells, neuronal survival, and immune tolerance. HGF is secreted as a propeptide that is activated by uPA or HGF Activator at sites of tissue damage. Its signaling through the receptor HGF R/c-MET is enhanced by its prior binding to heparan sulfate proteoglycans. The serum levels of HGF are elevated in a wide range of pathologies including liver damage, acute kidney failure, myocardial infarction, type 1 diabetes, obesity, and cancer, as well as in the synovial fluid of rheumatoid arthritis patients.

We have publications tested in 2 confirmed species: Mouse, Rat.

Showing Publications 1 - 10 of 29. Show All 29 Publications. Collapse Publications.

Publications using MHG00	Applications	Species
Saito, R;Inagaki, A;Nakamura, Y;Imura, T;Kanai, N;Mitsugashira, H;Endo, Y;Katano, T;Suzuki, S;Tokodai, K;Kamei, T;Unno, M;Watanabe, K;Tabata, Y;Goto, M; Ideal Duration of Pretreatment Using a Gelatin Hydrogel Nonwoven Fabric Prior to Subcutaneous Islet Transplantation Cell transplantation 2023-07-19 [PMID: 37466120] (Mouse)		Mouse
Okui, T;Hiasa, M;Hata, K;Roodman, GD;Nakanishi, M;Yoneda, T; The acid-sensing nociceptor TRPV1 controls breast cancer progression in bone via regulating HGF secretion from sensory neurons Research square 2023-07-05 [PMID: 37461623] (Mouse)		Mouse
Kojima, H;Kushige, H;Yagi, H;Nishijima, T;Moritoki, N;Nagoshi, N;Nakano, Y;Tanaka, M;Hori, S;Hasegawa, Y;Abe, Y;Kitago, M;Nakamura, M;Kitagawa, Y; Combinational Treatment Involving Decellularized Extracellular Matrix Hydrogels With Mesenchymal Stem Cells Increased the Efficacy of Cell Therapy in Pancreatitis Cell transplantation 2023-05-16 [PMID: 37191199] (Rat)		Rat
Y Iso, S Usui, H Suzuki Mesenchymal Stem/Stromal Cells in Skeletal Muscle Are Pro-Angiogenic, and the Effect Is Potentiated by Erythropoietin Pharmaceutics, 2023-03-24;15(4):. 2023-03-24 [PMID: 37111534] (Rat)		Rat
H Masuo, A Shimizu, H Motoyama, K Kubota, T Notake, T Yoshizawa, K Hosoda, K Yasukawa, A Kobayashi, Y Soejima Impact of endothelial nitric oxide synthase activation on accelerated liver regeneration in a rat ALPPS model World Journal of Gastroenterology, 2023-02-07;29(5):867-878. 2023-02-07 [PMID: 36816620] (Rat)		Rat
M Soltani, M Pourfarzam, AH Sharifabad, AK Neisiani, MK Mousavi, M Aliomrani Effect of pretreatment with a synbiotic on Perfluorooctanoic acid-induced liver damage after sub-acute oral exposure in C57BL/6J mice Toxicology and Applied Pharmacology, 2022-12-23;459(0):116360. 2022-12-23 [PMID: 36572227] (Mouse)		Mouse
T Suzuka, T Kotani, T Saito, S Matsuda, T Sato, T Takeuchi Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis Arthritis Research & Therapy, 2022-10-07;24(1):228. 2022-10-07 [PMID: 36207753] (Mouse)		Mouse
Y Matsuno, M Yanagihara, K Ueno, T Saito, H Kurazumi, R Suzuki, S Katsura, A Oga, K Hamano Dry preserved multilayered fibroblast cell sheets are a new manageable tool for regenerative medicine to promote wound healing Scientific Reports, 2022-07-22;12(1):12519. 2022-07-22 [PMID: 35869108] (Mouse)		Mouse
JH Jun, S Park, JY Kim, JY Lim, GT Park, JH Kim, GJ Kim Combination Therapy of Placenta-Derived Mesenchymal Stem Cells with WKYMVm Promotes Hepatic Function in a Rat Model with Hepatic Disease via Vascular Remodeling Cells, 2022-01-11;11(2):. 2022-01-11 [PMID: 35053347] (Rat)		Rat
H Nagano, Y Suematsu, M Takuma, S Aoki, A Satoh, E Takayama, M Kinoshita, Y Morimoto, S Takeoka, T Fujie, T Kiyosawa Enhanced cellular engraftment of adipose-derived mesenchymal stem cell spheroids by using nanosheets as scaffolds Scientific Reports, 2021-07-14;11(1):14500. 2021-07-14 [PMID: 34262089] (Mouse)		Mouse
R Zhang, J Jiang, Y Yu, F Wang, N Gao, Y Zhou, X Wan, Z Wang, P Wei, J Mei Analysis of structural components of decellularized scaffolds in renal fibrosis Bioactive materials, 2021-01-16;6(7):2187-2197. 2021-01-16 [PMID: 33511316] (Rat)		Rat
T Saito, T Kotani, K Suzuki Antifibrotic therapy by sustained release of low molecular weight heparin from poly(lactic-co-glycolic acid) microparticles on bleomycin-induced pulmonary fibrosis in mice Sci Rep, 2020-11-04;10(1):19019. 2020-11-04 [PMID: 33149192] (Mouse)		Mouse
GW Park, J Heo, JY Kang, JW Yang, JS Kim, KD Kwon, BC Yu, SJ Lee Topical cell-free conditioned media harvested from adipose tissue-derived stem cells promote recovery from corneal epithelial defects caused by chemical burns Sci Rep, 2020-07-24;10(1):12448. 2020-07-24 [PMID: 32709896] (Rat)		Rat
H Watanabe, S Goto, R Kato, S Komiyama, Y Nagaoka, T Kazama, C Yamamoto, Y Li, N Konuma, K Hagikura, T Matsumoto The neovascularization effect of dedifferentiated fat cells Sci Rep, 2020-06-08;10(1):9211. 2020-06-08 [PMID: 32514018] (Mouse)		Mouse
F Rohn, C Kordes, T Buschmann, D Reichert, M Wammers, G Poschmann, K Stühler, AS Benk, F Geiger, JP Spatz, D Häussinger Impaired integrin &alpha5 /&beta1 -mediated hepatocyte growth factor release by stellate cells of the aged liver Aging Cell, 2020-03-11;0(0):e13131. 2020-03-11 [PMID: 32157808] (Rat)		Rat
BL Ecker, JY Lee, CJ Sterner, AC Solomon, DK Pant, F Shen, J Peraza, L Vaught, S Mahendra, GK Belka, TC Pan, KH Schmitz, LA Chodosh Impact of obesity on breast cancer recurrence and minimal residual disease Breast Cancer Res., 2019-03-13;21(1):41. 2019-03-13 [PMID: 30867005] (Mouse)		Mouse
J Tang, J Wang, K Huang, Y Ye, T Su, L Qiao, MT Hensley, TG Caranasos, J Zhang, Z Gu, K Cheng Cardiac cell-integrated microneedle patch for treating myocardial infarction Sci Adv, 2018-11-28;4(11):eaat9365. 2018-11-28 [PMID: 30498778] (Rat)		Rat
X Chen, Y Zhang, W Wang, Z Liu, J Meng, Z Han Mesenchymal Stem Cells Modified with Heme Oxygenase-1 Have Enhanced Paracrine Function and Attenuate Lipopolysaccharide-Induced Inflammatory and Oxidative Damage in Pulmonary Microvascular Endothelial Cells Cell. Physiol. Biochem., 2018-08-28;49(1):101-122. 2018-08-28 [PMID: 30153667] (Rat)		Rat
ME Alvarèz Fa, M Piccoli, C Franzin, A Sgrò, A Dedja, L Urbani, E Bertin, C Trevisan, P Gamba, AJ Burns, P De Coppi, M Pozzobon Decellularized Diaphragmatic Muscle Drives a Constructive Angiogenic Response In Vivo Int J Mol Sci, 2018-04-28;19(5):. 2018-04-28 [PMID: 29710813] (Mouse)		Mouse
M Ahmed, G Kumar, S Gourevitch, T Levchenko, E Galun, V Torchilin, SN Goldberg Radiofrequency ablation (RFA) induced systemic tumor growth can be reduced by suppression of resultant heat shock proteins Int J Hyperthermia, 2018-04-24;0(0):1-25. 2018-04-24 [PMID: 29631466] (Rat)		Rat
YY Zhang, C Li, GF Yao, LJ Du, Y Liu, XJ Zheng, S Yan, JY Sun, Y Liu, MZ Liu, X Zhang, G Wei, W Tong, X Chen, Y Wu, S Sun, S Liu, Q Ding, Y Yu, H Yin, SZ Duan Deletion of Macrophage Mineralocorticoid Receptor Protects Hepatic Steatosis and Insulin Resistance through ER?/HGF/MET Pathway Diabetes, 2017-03-21;0(0):. 2017-03-21 [PMID: 28325853] (Mouse)		Mouse
Disrupting the blood-brain barrier by focused ultrasound induces sterile inflammation Proc. Natl. Acad. Sci. U.S.A, 2016-12-19;0(0):. 2016-12-19 [PMID: 27994152] (Rat)		Rat
First steps to define murine amniotic fluid stem cell microenvironment Sci Rep, 2016-11-15;6(0):37080. 2016-11-15 [PMID: 27845396] (Mouse)		Mouse
BubR1 Insufficiency Impairs Liver Regeneration in Aged Mice after Hepatectomy through Intercalated Disc Abnormality Sci Rep, 2016-08-26;6(0):32399. 2016-08-26 [PMID: 27561386] (Mouse)		Mouse
Raymond W, Xu X, Nimishakavi S, Le C, McDonald D, Caughey G Regulation of hepatocyte growth factor in mice with pneumonia by peptidases and trans-alveolar flux. PLoS ONE, 2015-05-04;10(5):e0125797. 2015-05-04 [PMID: 25938594] (Mouse)		Mouse
Cohen N, Zeng S, Seifert A, Kim T, Sorenson E, Greer J, Beckman M, Santamaria-Barria J, Crawley M, Green B, Rossi F, Besmer P, Antonescu C, DeMatteo R Pharmacological Inhibition of KIT Activates MET Signaling in Gastrointestinal Stromal Tumors. Cancer Res, 2015-04-02;75(10):2061-70. 2015-04-02 [PMID: 25836719] (Mouse)		Mouse
Ju , Guan-qun, Cheng , Jun, Zhong , Liang, Wu , Shuai, Zou , Xiang-yu, Zhang , Guang-yu, Gu , Di, Miao , Shuai, Zhu , Ying-jia, Sun , Jie, Du , Tao Microvesicles derived from human umbilical cord mesenchymal stem cells facilitate tubular epithelial cell dedifferentiation and growth via hepatocyte growth factor induction. PLoS ONE, 2015-03-20;10(3):e0121534. 2015-03-20 [PMID: 25793303] (Rat)		Rat
The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2. Sci Rep, 2015-03-04;5(0):8713. 2015-03-04 [PMID: 25736907] (Rat)		Rat
Garg R, Rennert R, Duscher D, Sorkin M, Kosaraju R, Auerbach L, Lennon J, Chung M, Paik K, Nimpf J, Rajadas J, Longaker M, Gurtner G Capillary force seeding of hydrogels for adipose-derived stem cell delivery in wounds. Stem Cells Transl Med, 2014-07-18;3(9):1079-89. 2014-07-18 [PMID: 25038246] (Mouse)		Mouse
Show All 29 Publications. Collapse Publications.

Array MHG00

• HGF Antibodies
• HGF ELISA Kits
• HGF Lysate
• HGF Proteins
• HGF ELISAs
• HGF Proteins and Enzymes