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Mouse IL-4 DuoSet ELISA, 15 Plate

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Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

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Mouse IL-4 DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il4

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DY404 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-4 DuoSet ELISA, 15 Plate

  • B cell growth factor 1
  • BCDF
  • B-cell stimulatory factor 1
  • BCGF1
  • BCGF-1
  • binetrakin
  • BSF1
  • BSF-1
  • IL4
  • IL-4
  • IL-4B_cell stimulatory factor 1
  • IL4E12
  • interleukin 4
  • interleukin-4
  • Lymphocyte stimulatory factor 1
  • MGC79402
  • pitrakinra

Background

IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R? and the common ? chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R? and IL-13 R?1. The type II receptor also transduces IL-13 mediated signals.

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Publications for IL-4 (DY404)(142)

We have publications tested in 3 confirmed species: Mouse, Transgenic Mouse, Transgenic Rat.

We have publications tested in 1 application: ELISA Standard.


Filter By Application
ELISA Standard
(1)
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Filter By Species
Mouse
(141)
Transgenic Mouse
(1)
Transgenic Rat
(1)
All Species
Showing Publications 1 - 10 of 142. Show All 142 Publications.
Publications using DY404 Applications Species
Raggi, C;Spadaro, F;Mattei, F;Gambardella, AR;Noto, F;Andreone, S;Signore, M;Schiavoni, G;Parolini, I;Afferni, C; Eosinophil-Airway Epithelial Cells crosstalk reveals the eosinophils-mediated DUOX1 up-regulation in a murine allergic inflammation setting Journal of leukocyte biology 2024-10-24 [PMID: 39447011] (Mouse) Mouse
Hussain, S;Majumder, N;Mazumder, MHH;Lewis, SE;Olapeju, O;Velayutham, M;Amin, MS;Brundage, K;Kelley, EE;Vanoirbeek, J; Intermittent ozone inhalation during house dust mite-induced sensitization primes for adverse asthma phenotype Redox biology 2024-10-01 [PMID: 39244793] (Mouse) Mouse
Taheri, M;Tehrani, HA;Farzad, SA;Korourian, A;Arefian, E;Ramezani, M; The potential of mesenchymal stem cell coexpressing cytosine deaminase and secretory IL18-FC chimeric cytokine in suppressing glioblastoma recurrence International immunopharmacology 2024-09-04 [PMID: 39236459] (Mouse) Mouse
Mohd Kasim, VNK;Lee, YZ;Bakrin, IH;Hussain, MK;Israf, DA;Shaari, K;Tan, JW;Lee, MT;Tham, CL; Oral and topical administration of a geranyl acetophenone attenuates DNCB-induced atopic dermatitis-like skin lesions in BALB/c mice Scientific reports 2024-07-31 [PMID: 39085287] (Mouse) Mouse
Pourhashem, Z;Nourani, L;Pirahmadi, S;Yousefi, H;J Sani, J;Raz, A;Zakeri, S;Dinparast Djadid, N;Abouie Mehrizi, A; Malaria transmission blocking activity of Anopheles stephensi alanyl aminopeptidase N antigen formulated with MPL, CpG, and QS21 adjuvants PloS one 2024-07-05 [PMID: 38968270] (Mouse) Mouse
Wu, Y;Adeniyi-Ipadeola, G;Adkins-Threats, M;Seasock, M;Suarez-Reyes, C;Fujiwara, R;Bottazzi, ME;Song, L;Mills, JC;Weatherhead, JE; Host gastric corpus microenvironment facilitates Ascaris suum larval hatching and infection in a murine model PLoS neglected tropical diseases 2024-02-01 [PMID: 38324590] (Mouse) Mouse
De, M;Sukla, S;Bharatiya, S;Keshri, S;Roy, DG;Roy, S;Dutta, D;Saha, S;Ejazi, SA;Ravichandiran, V;Ali, N;Chatterjee, M;Chinnaswamy, S; IFN-?3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans Infection and immunity 2024-01-09 [PMID: 38193711] (Mouse) Mouse
Zhang, H;Xue, K;Li, W;Yang, X;Gou, Y;Su, X;Qian, F;Sun, L; Cullin5 drives experimental asthma exacerbations by modulating alveolar macrophage antiviral immunity Nature communications 2024-01-04 [PMID: 38177117] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
Shahbazi, S;Habibi, M;Badmasti, F;Sabzi, S;Farokhi, M;Asadi Karam, MR; Design and fabrication of a vaccine candidate based on rOmpA from Klebsiella pneumoniae encapsulated in silk fibroin-sodium alginate nanoparticles against pneumonia infection International immunopharmacology 2023-11-08 [PMID: 37948863] (Mouse) Mouse
Su, HH;Cheng, CM;Yang, YN;Chang, YW;Li, CY;Wu, ST;Lin, CC;Wu, HE;Suen, JL; Acrylamide, an Air Pollutant, Enhances Allergen-Induced Eosinophilic Lung Inflammation via Group 2 Innate Lymphoid Cells Mucosal immunology 2023-10-05 [PMID: 37805143] (Mouse) Mouse
Show All 142 Publications.

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By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...  Read full blog post.

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Bioinformatics

Gene Symbol Il4