Mouse IL-1 alpha/IL-1F1 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

IL-1 alpha (Interleukin-1 alpha) is a cytokine that is induced during microbial exposure and promotes the release of multiple inflammatory mediators and acute phase proteins. It also supports hematopoietic stem cell expansion, promotes neutrophil mobilization from the bone marrow, and promotes osteoclast formation. IL-1 alpha signals through a receptor complex composed of IL-1 RI and IL-1 RAcP. It also binds the decoy receptor IL-1 RII which associates with IL-1 RAcP but does not transduce signaling.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 10 of 33. Show All 33 Publications. Collapse Publications.

Publications using MLA00	Applications	Species
Ko, JS;Chang, BY;Choi, YJ;Choi, JS;Kwon, HY;Lee, JY;Kim, SY;Choung, SY; Ashwagandha Ethanol Extract Attenuates Sarcopenia-Related Muscle Atrophy in Aged Mice Nutrients 2024-01-03 [PMID: 38201986] (Mouse)		Mouse
Jiang, SY;Tian, T;Yao, H;Xia, XM;Wang, C;Cao, L;Hu, G;Du, RH;Lu, M; The cGAS-STING-YY1 axis accelerates progression of neurodegeneration in a mouse model of Parkinson's disease via LCN2-dependent astrocyte senescence Cell death and differentiation 2023-08-26 [PMID: 37633968] (Mouse)		Mouse
GK Vivian, RO da Silva, ACA Santos, AA Hastreiter, CC Dias, EN Makiyama, P Borelli, C de Oliveir, RA Fock The interaction between aging and protein malnutrition modulates peritoneal macrophage function: An experimental study in male mice Experimental gerontology, 2022-11-11;171(0):112025. 2022-11-11 [PMID: 36372284] (Mouse)		Mouse
M Kamiya, F Mizoguchi, K Kawahata, D Wang, M Nishibori, J Day, C Louis, IP Wicks, H Kohsaka, S Yasuda Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies Nature Communications, 2022-01-10;13(1):166. 2022-01-10 [PMID: 35013338] (Mouse)		Mouse
P Innamarato, J Morse, A Mackay, S Asby, M Beatty, J Blauvelt, S Kidd, JE Mullinax, AA Sarnaik, S Pilon-Thom Intralesional injection of rose bengal augments the efficacy of gemcitabine chemotherapy against pancreatic tumors BMC Cancer, 2021-06-30;21(1):756. 2021-06-30 [PMID: 34187428] (Mouse)		Mouse
A Matsunami, M Mizuno-Kam, H Kawaki, E Takayama, K Ueno, M Ando, H Morimoto-I, Y Muramatsu, S Sumitomo, N Kondoh Augmented secretion of IL-1&alpha from mouse oral squamous cell carcinoma (OSCC) cells caused by serum deprivation and hypoxia promotes immune suppressive activity of mesenchymal stromal cells Journal of oral biosciences, 2021-06-18;0(0):. 2021-06-18 [PMID: 34153475] (Mouse)		Mouse
A Tripathi, C Whitehead, K Surrao, A Pillai, A Madeshiya, Y Li, H Khodadadi, AO Ahmed, G Turecki, B Baban, A Pillai Type 1 interferon mediates chronic stress-induced neuroinflammation and behavioral deficits via complement component 3-dependent pathway Molecular Psychiatry, 2021-04-08;0(0):. 2021-04-08 [PMID: 33833372] (Mouse)		Mouse
JJ Collier, HM Batdorf, TM Martin, KE Rohli, DH Burk, D Lu, CR Cooley, MD Karlstad, JW Jackson, TE Sparer, J Zhang, RL Mynatt, SJ Burke Pancreatic, but not myeloid-cell, expression of interleukin-1alpha is required for maintenance of insulin secretion and whole body glucose homeostasis Molecular Metabolism, 2020-12-05;44(0):101140. 2020-12-05 [PMID: 33285301] (Mouse)		Mouse
Z Li, J Wang, B Zheng, Z Guo Impact of combined ultrasound-microwave treatment on structural and functional properties of golden threadfin bream (Nemipterus virgatus) myofibrillar proteins and hydrolysates Ultrason Sonochem, 2020-03-09;65(0):105063. 2020-03-09 [PMID: 32199256] (Mouse)		Mouse
IJ Yeo, MJ Lee, A Baek, Z Miller, D Bhattarai, YM Baek, HJ Jeong, YK Kim, DE Kim, JT Hong, KB Kim A dual inhibitor of the proteasome catalytic subunits LMP2 and Y attenuates disease progression in mouse models of Alzheimer's disease Sci Rep, 2019-12-05;9(1):18393. 2019-12-05 [PMID: 31804556] (Mouse)		Mouse
N Guo, V DeAngelis, C Zhu, EH Schuchman, CM Simonaro Pentosan Polysulfate Treatment of Mucopolysaccharidosis Type IIIA Mice JIMD Rep, 2018-04-14;0(0):. 2018-04-14 [PMID: 29654542] (Mouse)		Mouse
G Hanouna, L Mesnard, S Vandermeer, J Perez, S Placier, JP Haymann, F Campagne, J Moroch, A Bataille, L Baud, E Letavernie Specific calpain inhibition protects kidney against inflammaging Sci Rep, 2017-08-14;7(1):8016. 2017-08-14 [PMID: 28808241] (Mouse)		Mouse
Kruppel-like factor 6 promotes macrophage-mediated inflammation by suppressing B cell leukemia/lymphoma 6 expression J Biol Chem, 2016-08-18;0(0):. 2016-08-18 [PMID: 27539853] (Mouse)		Mouse
Meng L, Jin W, Wang X RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality. Proc Natl Acad Sci U S A, 2015-08-17;112(35):11007-12. 2015-08-17 [PMID: 26283397] (Mouse)		Mouse
Schonberger T, Jurgens T, Muller J, Armbruster N, Niermann C, Gorressen S, Sommer J, Tian H, di Paolo G, Scheller J, Fischer J, Gawaz M, Elvers M Pivotal role of phospholipase D1 in tumor necrosis factor-alpha-mediated inflammation and scar formation after myocardial ischemia and reperfusion in mice. Am J Pathol, 2014-07-18;184(9):2450-64. 2014-07-18 [PMID: 25046692] (Mouse)		Mouse
de Oliveira D, Hastreiter A, Mello A, de Oliveira Beltran J, Oliveira Santos E, Borelli P, Fock R The effects of protein malnutrition on the TNF-RI and NF-kappaB expression via the TNF-alpha signaling pathway. Cytokine, 2014-07-06;69(2):218-25. 2014-07-06 [PMID: 25005154] (Mouse)		Mouse
Thongchote K, Svasti S, Teerapornpuntakit J, Krishnamra N, Charoenphandhu N Running exercise alleviates trabecular bone loss and osteopenia in hemizygous beta-globin knockout thalassemic mice. Am J Physiol Endocrinol Metab, 2014-04-29;306(12):E1406-17. 2014-04-29 [PMID: 24780610] (Mouse)		Mouse
Vital P, Castro P, Tsang S, Ittmann M The senescence-associated secretory phenotype promotes benign prostatic hyperplasia. Am J Pathol, 2014-01-13;184(3):721-31. 2014-01-13 [PMID: 24434012] (Mouse)		Mouse
Drexler , Stefan K, Bonsignore , Luca, Masin , Mark, Tardivel , Aubry, Jackstadt , Rene, Hermeking , Heiko, Schneider , Pascal, Gross , Olaf, Tschopp , Jurg, Yazdi , Amir S Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis. Proc Natl Acad Sci U S A, 2012-10-22;109(45):18384-9. 2012-10-22 [PMID: 23090995] (Mouse)		Mouse
Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner. Blood, 2012-07-17;120(13):2600-9. 2012-07-17 [PMID: 22806894] (Mouse)		Mouse
Luheshi NM, Giles JA, Lopez-Castejon G, Brough D Sphingosine regulates the NLRP3-inflammasome and IL-1beta release from macrophages. Eur. J. Immunol., 2011-12-27;42(3):716-25. 2011-12-27 [PMID: 22105559] (Mouse)		Mouse
Pauwels NS, Bracke KR, Dupont LL, Van Pottelberge GR, Provoost S, Vanden Berghe T, Vandenabeele P, Lambrecht BN, Joos GF, Brusselle GG Role of IL-1alpha and the Nlrp3/caspase-1/IL-1beta axis in cigarette smoke-induced pulmonary inflammation and COPD. Eur. Respir. J., 2011-05-26;38(5):1019-28. 2011-05-26 [PMID: 21622588] (Mouse)		Mouse
Wang H, Cheng F Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10. J. Immunol., 2011-03-02;186(0):3986. 2011-03-02 [PMID: 21368229] (Mouse)		Mouse
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nunez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes. Nat. Immunol., 2010-09-12;11(10):897-904. 2010-09-12 [PMID: 20835230] (Mouse)		Mouse
Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice. Cytokine, 2009-12-29;49(3):256-63. 2009-12-29 [PMID: 20042347] (Mouse)		Mouse
Surguladze D, Deevi D, Claros N, Corcoran E, Wang S, Plym MJ, Wu Y, Doody J, Mauro DJ, Witte L, Busam KJ, Pytowski B, Rodeck U, Tonra JR Tumor necrosis factor-alpha and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice. Cancer Res., 2009-07-07;69(14):5643-7. 2009-07-07 [PMID: 19584274] (Mouse)		Mouse
Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum. J. Immunol., 2009-06-19;183(2):1291-300. 2009-06-19 [PMID: 19542374] (Mouse)		Mouse
Bitko V, Musiyenko A, Barik S Viral infection of the lungs through the eye. J. Virol., 2006-10-18;81(2):783-90. 2006-10-18 [PMID: 17050596] (Mouse)		Mouse
Ishida Y, Kondo T, Kimura A, Matsushima K, Mukaida N Absence of IL-1 receptor antagonist impaired wound healing along with aberrant NF-kappaB activation and a reciprocal suppression of TGF-beta signal pathway. J. Immunol., 2006-05-01;176(9):5598-606. 2006-05-01 [PMID: 16622029] (Mouse)		Mouse
Wei S, Kitaura H, Zhou P, Ross FP, Teitelbaum SL IL-1 mediates TNF-induced osteoclastogenesis. J. Clin. Invest., 2005-02-01;115(2):282-90. 2005-02-01 [PMID: 15668736] (Mouse)		Mouse
Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes. Comp. Immunol. Microbiol. Infect. Dis., 2004-11-01;27(6):393-411. 2004-11-01 [PMID: 15325513] (Mouse)		Mouse
Hao Z, Hampel B, Yagita H, Rajewsky K T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis. J. Exp. Med., 2004-05-17;199(10):1355-65. 2004-05-17 [PMID: 15148335] (Mouse)		Mouse
Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls. Eur. J. Immunol., 2001-07-01;31(7):2104-15. 2001-07-01 [PMID: 11449364] (Mouse)		Mouse
Show All 33 Publications. Collapse Publications.

Array MLA00

• IL-1 alpha/IL-1F1 Antibodies
• IL-1 alpha/IL-1F1 Antibody Pair
• IL-1 alpha/IL-1F1 ELISA Kits
• IL-1 alpha/IL-1F1 Proteins
• IL-1 alpha/IL-1F1 ELISAs
• IL-1 alpha/IL-1F1 Proteins and Enzymes