Mouse IFN-beta Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

We have publications tested in 2 confirmed species: Mouse, Transgenic Mouse.

Showing Publications 1 - 10 of 24. Show All 24 Publications. Collapse Publications.

Publications using MIFNB0	Applications	Species
Deng, A;Fan, R;Hai, Y;Zhuang, J;Zhang, B;Lu, X;Wang, W;Luo, L;Bai, G;Liang, L;Yang, L;Zhao, M;Wei, G; A STING agonist prodrug reprograms tumor-associated macrophage to boost colorectal cancer immunotherapy Theranostics 2025-01-01 [PMID: 39744236] (Mouse)		Mouse
Ladak, RJ;Choi, JH;Luo, J;Chen, OJ;Mahmood, N;He, AJ;Naeli, P;Snell, PH;Bayani, E;Hoang, HD;Alain, T;Teodoro, JG;Wang, J;Zhang, X;Jafarnejad, SM;Sonenberg, N; The 4EHP-mediated translational repression of cGAS impedes the host immune response against DNA viruses Proceedings of the National Academy of Sciences of the United States of America 2024-11-26 [PMID: 39560640] (Transgenic Mouse)		Transgenic Mouse
Tripathi, A;Bartosh, A;Mata, J;Jacks, C;Madeshiya, AK;Hussein, U;Hong, LE;Zhao, Z;Pillai, A; Microglial type I interferon signaling mediates chronic stress-induced synapse loss and social behavior deficits Molecular psychiatry 2024-08-02 [PMID: 39095477] (Mouse)		Mouse
Leekha, A;Saeedi, A;Kumar, M;Sefat, KMSR;Martinez-Paniagua, M;Meng, H;Fathi, M;Kulkarni, R;Reichel, K;Biswas, S;Tsitoura, D;Liu, X;Cooper, LJN;Sands, CM;Das, VE;Sebastian, M;Hurst, BL;Varadarajan, N; An intranasal nanoparticle STING agonist protects against respiratory viruses in animal models Nature communications 2024-07-18 [PMID: 39025863] (Mouse)		Mouse
Wang, J;Jin, X;Yan, S;Zhao, H;Pang, D;Ouyang, H;Tang, X; Yeast ?-glucan promotes antiviral type I interferon response via dectin-1 Veterinary microbiology 2024-05-09 [PMID: 38838382] (Mouse)		Mouse
Yuen, CK;Wong, WM;Mak, LF;Lam, JY;Cheung, LY;Cheung, DT;Ng, YY;Lee, AC;Zhong, N;Yuen, KY;Kok, KH; An interferon-integrated mucosal vaccine provides pan-sarbecovirus protection in small animal models Nature communications 2023-10-24 [PMID: 37875475] (Mouse)		Mouse
Dossou, AS;Mantsch, ME;Kapic, A;Burnett, WL;Sabnis, N;Coffer, JL;Berg, RE;Fudala, R;Lacko, AG; Mannose-Coated Reconstituted Lipoprotein Nanoparticles for the Targeting of Tumor-Associated Macrophages: Optimization, Characterization, and In Vitro Evaluation of Effectiveness Pharmaceutics 2023-06-08 [PMID: 37376134] (Mouse)		Mouse
A Hooftman, CG Peace, DG Ryan, EA Day, M Yang, AF McGettrick, M Yin, EN Montano, L Huo, JE Toller-Kaw, V Zecchini, TAJ Ryan, A Bolado-Car, AM Casey, HA Prag, ASH Costa, G De Los San, M Ishimori, DJ Wallace, S Venuturupa, E Nikitopoul, N Frizzell, C Johansson, A Von Kriegs, MP Murphy, C Jefferies, C Frezza, LAJ O'Neill Macrophage fumarate hydratase restrains mtRNA-mediated interferon production Nature, 2023-03-08;615(7952):490-498. 2023-03-08 [PMID: 36890227] (Mouse)		Mouse
Q Zhou, Y Luo, Y Zhu, Q Chen, J Qiu, F Cong, Y Li, X Zhang Nonsteroidal anti-inflammatory drugs (NSAIDs) and nucleotide analog GS-441524 conjugates with potent in vivo efficacy against coronaviruses European Journal of Medicinal Chemistry, 2023-01-10;249(0):115113. 2023-01-10 [PMID: 36706621] (Mouse)		Mouse
M Hagihara, M Yamashita, T Ariyoshi, S Eguchi, A Minemura, D Miura, S Higashi, K Oka, T Nonogaki, T Mori, K Iwasaki, J Hirai, Y Shibata, T Umemura, H Kato, N Asai, Y Yamagishi, A Ota, M Takahashi, H Mikamo Clostridium butyricum-induced ?-3 fatty acid 18-HEPE elicits anti-influenza virus pneumonia effects through interferon-lambda upregulation Cell Reports, 2022-12-13;41(11):111755. 2022-12-13 [PMID: 36516771] (Mouse)		Mouse
TK Kim, S Jeon, S Park, SK Sonn, S Seo, J Suh, J Jin, HY Kweon, S Kim, SH Moon, O Kweon, BH Koo, N Kim, HO Lee, YM Kim, YJ Kim, SH Park, GT Oh 2'-5' oligoadenylate synthetase?like 1 (OASL1) protects against atherosclerosis by maintaining endothelial nitric oxide synthase mRNA stability Nature Communications, 2022-11-04;13(1):6647. 2022-11-04 [PMID: 36333342] (Mouse)		Mouse
M Tomokiyo, FR Tonetti, H Yamamuro, R Shibata, K Fukuyama, N Gobbato, L Albarracin, MSR Rajoka, AKMH Kober, W Ikeda-Ohts, J Villena, H Kitazawa Modulation of Alveolar Macrophages by Postimmunobiotics: Impact on TLR3-Mediated Antiviral Respiratory Immunity Cells, 2022-09-25;11(19):. 2022-09-25 [PMID: 36230948] (Mouse)		Mouse
X Liu, W Luo, J Chen, C Hu, RN Mutsinze, X Wang, Y Zhang, L Huang, W Zuo, G Liang, Y Wang USP25 deficiency exacerbates acute pancreatitis via upregulating TBK1-NF-kappaB signaling in macrophages Cellular and Molecular Gastroenterology and Hepatology, 2022-08-04;0(0):. 2022-08-04 [PMID: 35934222] (Mouse)		Mouse
C Song, D Liu, S Liu, D Li, I Horecny, X Zhang, P Li, L Chen, M Miller, R Chowdhury, M Issa, R Shen, Y Yan, F Zhang, L Zhang, L Zhang, C Bai, J Feng, L Zhuang, R Zhang, J Li, H Wilkinson, J Liu, W Tao SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis Scientific Reports, 2022-05-20;12(1):8579. 2022-05-20 [PMID: 35595822] (Mouse)		Mouse
L Liang, Y Shen, Y Hu, H Liu, J Cao cGAS exacerbates Schistosoma japonicum infection in a STING-type I IFN-dependent and independent manner PloS Pathogens, 2022-02-02;18(2):e1010233. 2022-02-02 [PMID: 35108342] (Mouse)		Mouse
X Liu, L Lv, C Jiang, J Bai, Y Gao, Z Ma, P Jiang A natural product, (S)-10-Hydroxycamptothecin inhibits pseudorabies virus proliferation through DNA damage dependent antiviral innate immunity Veterinary Microbiology, 2021-12-20;265(0):109313. 2021-12-20 [PMID: 34968801] (Mouse)		Mouse
Y Hanada, N Ishihara, L Wang, H Otera, T Ishihara, T Koshiba, K Mihara, Y Ogawa, M Nomura MAVS is energized by Mff which senses mitochondrial metabolism via AMPK for acute antiviral immunity Nat Commun, 2020-11-11;11(1):5711. 2020-11-11 [PMID: 33177519] (Mouse)		Mouse
GB Kim, GH Nam, Y Hong, J Woo, Y Cho, IC Kwon, Y Yang, IS Kim Xenogenization of tumor cells by fusogenic exosomes in tumor microenvironment ignites and propagates antitumor immunity Science Advances, 2020-07-01;6(27):. 2020-07-01 [PMID: 32937446] (Mouse)		Mouse
C Ge, J Tan, S Zhong, L Lai, G Chen, J Zhao, C Yi, L Wang, L Zhou, T Tang, Q Yang, D Lou, Q Li, Y Wu, L Hu, G Kuang, X Liu, B Wang, M Xu Nrf2 mitigates prolonged PM2.5 exposure-triggered liver inflammation by positively regulating SIKE activity: Protection by Juglanin Redox Biol, 2020-07-17;36(0):101645. 2020-07-17 [PMID: 32863207] (Mouse)		Mouse
R Ueki, S Uchida, N Kanda, N Yamada, A Ueki, M Akiyama, K Toh, H Cabral, S Sando A chemically unmodified agonistic DNA with growth factor functionality for in vivo therapeutic application Sci Adv, 2020-04-01;6(14):eaay2801. 2020-04-01 [PMID: 32270033] (Mouse)		Mouse
Y Hattori, Y Naito, Y Tsugawa, S Nonaka, H Wake, T Nagasawa, A Kawaguchi, T Miyata Transient microglial absence assists postmigratory cortical neurons in proper differentiation Nat Commun, 2020-04-02;11(1):1631. 2020-04-02 [PMID: 32242005] (Mouse)		Mouse
C Quach, Y Song, H Guo, S Li, H Maazi, M Fung, N Sands, D O'Connell, S Restrepo-V, B Chai, D Nemecio, V Punj, O Akbari, GE Idos, SM Mumenthale, N Wu, SE Martin, A Hagiya, J Hicks, H Cui, C Liang A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice Nat Commun, 2019-12-12;10(1):5681. 2019-12-12 [PMID: 31831743] (Mouse)		Mouse
A Miyauchi, W Watanabe, T Akashi, S Hashiguchi, H Yoshida, C Sugita, M Kurokawa Effect of inactivated Streptococcus pneumoniae as non-pathogenic particles on the severity of pneumonia caused by respiratory syncytial virus infection in mice Toxicol Rep, 2019-05-31;6(0):514-520. 2019-05-31 [PMID: 31245279] (Mouse)		Mouse
JJ Ishizuka, RT Manguso, CK Cheruiyot, K Bi, A Panda, A Iracheta-V, BC Miller, PP Du, KB Yates, J Dubrot, I Buchumensk, DE Comstock, FD Brown, A Ayer, IC Kohnle, HW Pope, MD Zimmer, DR Sen, SK Lane-Retic, EJ Robitschek, GK Griffin, NB Collins, AH Long, JG Doench, D Kozono, EY Levanon, WN Haining Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade Nature, 2018-12-17;565(7737):43-48. 2018-12-17 [PMID: 30559380] (Mouse)		Mouse
Show All 24 Publications. Collapse Publications.

Array MIFNB0

• IFN-beta Antibodies
• IFN-beta ELISA Kits
• IFN-beta Lysate
• IFN-beta Proteins
• IFN-beta Proteins and Enzymes
• IFN-beta ELISAs