Mouse HGF DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

HGF (Hepatocyte Growth Factor, Scatter Factor) induces the proliferation and migration of epithelial cells, hepatocytes, chondrocytes, keratinocytes, melanocytes, endothelial cells, and many tumor cells. During organogenesis and tissue repair, HGF promotes epithelial/endothelial morphogenesis by inducing cell scattering and branching tubulogenesis. It also supports insulin production by pancreatic beta cells, neuronal survival, and immune tolerance. HGF is secreted as a propeptide that is activated by uPA or HGF Activator at sites of tissue damage. Its signaling through the receptor HGF R/c-MET is enhanced by its prior binding to heparan sulfate proteoglycans. The serum levels of HGF are elevated in a wide range of pathologies including liver damage, acute kidney failure, myocardial infarction, type 1 diabetes, obesity, and cancer, as well as in the synovial fluid of rheumatoid arthritis patients.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using DY2207	Applications	Species
A Filliol, Y Saito, A Nair, DH Dapito, LX Yu, A Ravichandr, S Bhattachar, S Affo, N Fujiwara, H Su, Q Sun, TM Savage, JR Wilson-Kan, JM Caviglia, L Chin, D Chen, X Wang, S Caruso, JK Kang, AD Amin, S Wallace, R Dobie, D Yin, OM Rodriguez-, C Yin, A Mehal, B Izar, RA Friedman, RG Wells, UB Pajvani, Y Hoshida, HE Remotti, N Arpaia, J Zucman-Ros, M Karin, NC Henderson, I Tabas, RF Schwabe Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis Nature, 2022-10-05;0(0):. 2022-10-05 [PMID: 36198802] (Mouse)		Mouse
J Faura, L Ramiro, A Simats, F Ma, A Penalba, T Gasull, A Rosell, J Montaner, A Bustamante Evaluation and Characterization of Post-Stroke Lung Damage in a Murine Model of Cerebral Ischemia International Journal of Molecular Sciences, 2022-07-22;23(15):. 2022-07-22 [PMID: 35897671] (Mouse)		Mouse
P Rozier, M Maumus, ATJ Maria, K Toupet, C Jorgensen, P Guilpain, D Noël Lung Fibrosis Is Improved by Extracellular Vesicles from IFNgamma-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis Cells, 2021-10-13;10(10):. 2021-10-13 [PMID: 34685707] (Mouse)		Mouse
Y Ikegami, H Mizumachi, K Yoshida, H Ijima Heparin-conjugated collagen as a potent growth factor-localizing and stabilizing scaffold for regenerative medicine Regenerative Therapy, 2020-11-01;15(0):236-242. 2020-11-01 [PMID: 33426224] (Mouse)		Mouse
M Mastri, CR Lee, A Tracz, RS Kerbel, M Dolan, Y Shi, JML Ebos Tumor-independent host secretomes induced by angiogenesis and immune-checkpoint inhibitors Mol. Cancer Ther., 2018-04-25;0(0):. 2018-04-25 [PMID: 29695634] (Mouse)		Mouse
Koliaraki V, Roulis M, Kollias G Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis. J Clin Invest, 2012-10-15;122(11):4231-42. 2012-10-15 [PMID: 23064365] (Mouse)		Mouse
Facciabene A, Peng X, Hagemann IS, Balint K, Barchetti A, Wang LP, Gimotty PA, Gilks CB, Lal P, Zhang L, Coukos G Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature, 2011-07-13;475(7355):226-30. 2011-07-13 [PMID: 21753853] (Mouse)		Mouse
Gordin M, Tesio M, Cohen S c-Met and its ligand hepatocyte growth factor/scatter factor regulate mature B cell survival in a pathway induced by CD74. J. Immunol., 2010-07-16;185(4):2020-31. 2010-07-16 [PMID: 20639480] (Mouse)		Mouse
Wu Y, Li YY, Matsushima K, Baba T, Mukaida N CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process. J. Immunol., 2008-11-01;181(9):6384-93. 2008-11-01 [PMID: 18941229] (Mouse)		Mouse
Ren X, Hu B, Colletti L Stem cell factor and its receptor, c-kit, are important for hepatocyte proliferation in wild-type and tumor necrosis factor receptor-1 knockout mice after 70% hepatectomy. Surgery, 2008-06-01;143(6):790-802. 2008-06-01 [PMID: 18549896] (Mouse)		Mouse
Natarajan A, Wagner B, Sibilia M The EGF receptor is required for efficient liver regeneration. Proc. Natl. Acad. Sci. U.S.A., 2007-10-16;104(43):17081-6. 2007-10-16 [PMID: 17940036] (Mouse)		Mouse
Show All 11 Publications. Collapse Publications.

Array DY2207

• HGF Antibodies
• HGF ELISA Kits
• HGF Lysate
• HGF Proteins
• HGF ELISAs
• HGF Proteins and Enzymes