Mouse G-CSF DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Mouse granulocyte-colony stimulating factor (G-CSF) is a 24-25 kDa monomeric glycoprotein that regulates the proliferation, differentiation and activation of hematopoietic cells. Mouse G-CSF cDNA encodes a 208 amino acid (aa) precursor protein with a 30 aa signal sequence that is proteolytically cleaved to form a 178 aa O-glycosylated mature protein containing two intrachain disulfide bridges. In humans, two distinct cDNA clones, encoding a 204 aa form and a minor alternatively spliced 207 aa form of G-CSF precursors, have been isolated. Mouse and human G-CSF are 76% identical at the aa sequence level and the two proteins show species cross-reactivity. G-CSF is produced primarily by monocytes and macrophages upon activation by endotoxin, TNF-alpha or IL-1. Other cell types, including fibroblasts, endothelial cells, astrocytes and bone marrow stroma cells, can also secrete G-CSF after activation. In addition, various tumor cells express G-CSF constitutively.   

We have publications tested in 2 confirmed species: Mouse, Transgenic Mouse.

Showing Publications 1 - 10 of 29. Show All 29 Publications. Collapse Publications.

Publications using DY414	Applications	Species
Flores-Valdez, MA;Peterson, EJR;Aceves-Sánchez, MJ;Baliga, NS;Morita, YS;Sparks, IL;Saini, DK;Yadav, R;Lang, R;Mata-Espinosa, D;León-Contreras, JC;Hernández-Pando, R; Comparison of the transcriptome, lipidome, and c-di-GMP production between BCG?BCG1419c and BCG, with Mincle- and Myd88-dependent induction of proinflammatory cytokines in murine macrophages Scientific reports 2024-05-24 [PMID: 38789479] (Mouse, Transgenic Mouse)		Mouse, Transgenic Mouse
Kinsella, RL;Kimmey, JM;Smirnov, A;Woodson, R;Gaggioli, MR;Chavez, SM;Kreamalmeyer, D;Stallings, CL; Autophagy prevents early proinflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen burden in macrophages PLoS biology 2023-06-15 [PMID: 37319285] (Mouse)		Mouse
N Ikeda, H Kubota, R Suzuki, M Morita, A Yoshimura, Y Osada, K Kishida, D Kitamura, A Iwata, S Yotsumoto, D Kurotaki, K Nishimura, A Nishiyama, T Tamura, T Kamatani, T Tsunoda, M Murakawa, Y Asahina, Y Hayashi, H Harada, Y Harada, A Yokota, H Hirai, T Seki, M Kuwahara, M Yamashita, S Shichino, M Tanaka, K Asano The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis Cell Reports, 2023-02-28;42(3):112165. 2023-02-28 [PMID: 36862552] (Mouse)		Mouse
P Selvam, CM Cheng, HU Dahms, VK Ponnusamy, YY Sun AhR Mediated Activation of Pro-Inflammatory Response of RAW 264.7 Cells Modulate the Epithelial-Mesenchymal Transition Toxics, 2022-10-27;10(11):. 2022-10-27 [PMID: 36355934] (Mouse)		Mouse
M Kokoszynsk, ND Ubags, JJ Bivona, S Ventrone, LF Reed, AE Dixon, MJ Wargo, ME Poynter, BT Suratt Storage conditions of high-fat diets affect pulmonary inflammation Physiological Reports, 2021-11-01;9(22):e15116. 2021-11-01 [PMID: 34822216] (Mouse)		Mouse
JH Song, DY Eum, SY Park, YH Jin, JW Shim, SJ Park, MY Kim, SJ Park, K Heo, YJ Choi Inhibitory effect of ginsenoside Rg3 on cancer stemness and mesenchymal transition in breast cancer via regulation of myeloid-derived suppressor cells PLoS ONE, 2020-10-22;15(10):e0240533. 2020-10-22 [PMID: 33091036] (Mouse)		Mouse
AL Aldrich, CE Heim, W Shi, RW Fallet, B Duan, T Kielian TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection J Neuroinflammation, 2020-04-14;17(1):114. 2020-04-14 [PMID: 32290861] (Mouse)		Mouse
NE Powers, B Swartzwelt, C Marchetti, DM de Graaf, A Lerchner, M Schlapschy, R Datar, U Binder, CK Edwards, A Skerra, CA Dinarello PASylation of IL-1 Receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis J. Biol. Chem., 2019-12-09;0(0):. 2019-12-09 [PMID: 31819009] (Mouse)		Mouse
S Lorscheid, A Müller, J Löffler, C Resch, P Bucher, FC Kurschus, A Waisman, K Schäkel, S Hailfinger, K Schulze-Os, D Kramer Keratinocyte-derived I&kappaB? drives psoriasis and associated systemic inflammation JCI Insight, 2019-11-14;4(22):. 2019-11-14 [PMID: 31622280] (Mouse)		Mouse
BE Hsu, S Tabariès, RM Johnson, S Andrzejews, J Senecal, C Lehuédé, MG Annis, EH Ma, S Völs, L Ramsay, R Froment, A Monast, IR Watson, Z Granot, RG Jones, J St-Pierre, PM Siegel Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis Cell Rep, 2019-06-25;27(13):3902-3915.e6. 2019-06-25 [PMID: 31242422] (Mouse)		Mouse
MA Meyer, JM Baer, BL Knolhoff, TM Nywening, RZ Panni, X Su, KN Weilbaeche, WG Hawkins, C Ma, RC Fields, DC Linehan, GA Challen, R Faccio, RL Aft, DG DeNardo Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance Nat Commun, 2018-03-28;9(1):1250. 2018-03-28 [PMID: 29593283] (Mouse)		Mouse
I Mitroulis, K Ruppova, B Wang, LS Chen, M Grzybek, T Grinenko, A Eugster, M Troullinak, A Palladini, I Kourtzelis, A Chatzigeor, A Schlitzer, M Beyer, LAB Joosten, B Isermann, M Lesche, A Petzold, K Simons, I Henry, A Dahl, JL Schultze, B Wielockx, N Zamboni, P Mirtschink, Ü Coskun, G Hajishenga, MG Netea, T Chavakis Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity Cell, 2018-01-11;172(1):147-161.e12. 2018-01-11 [PMID: 29328910] (Mouse)		Mouse
MS Gresnigt, M Jaeger, RK Subbarao M, O Rasid, G Jouvion, C Fitting, WJG Melchers, TD Kanneganti, A Carvalho, O Ibrahim-Gr, FL van de Vee The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression Front Immunol, 2017-12-13;8(0):1777. 2017-12-13 [PMID: 29326692] (Mouse)		Mouse
I Mitroulis, LS Chen, RP Singh, I Kourtzelis, M Economopou, T Kajikawa, M Troullinak, A Ziogas, K Ruppova, K Hosur, T Maekawa, B Wang, P Subramania, T Tonn, P Verginis, M von Bonin, M Wobus, M Bornhäuser, T Grinenko, M Di Scala, A Hidalgo, B Wielockx, G Hajishenga, T Chavakis Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche J. Clin. Invest., 2017-08-28;0(0):. 2017-08-28 [PMID: 28846069] (Mouse)		Mouse
Extracellular Superoxide Dismutase Enhances the Recruitment of Immature Neutrophils to the Liver Infect Immun, 2016-11-18;0(0):. 2016-11-18 [PMID: 27600509] (Mouse)		Mouse
Epidermal RAF prevents allergic skin disease Elife, 2016-07-19;5(0):. 2016-07-19 [PMID: 27431613] (Mouse)		Mouse
The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment EMBO Mol Med, 2016-08-01;0(0):. 2016-08-01 [PMID: 27226028] (Mouse)		Mouse
Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor Sci Rep, 2016-05-24;6(0):26490. 2016-05-24 [PMID: 27215684] (Mouse)		Mouse
A Savers, O Rasid, M Parlato, M Brock, G Jouvion, B Ryffel, JM Cavaillon, G Eberl, O Ibrahim-Gr Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge PLoS ONE, 2016-04-14;11(4):e0153829. 2016-04-14 [PMID: 27078879] (Mouse)		Mouse
Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, Gregory A, Kochman E, Chen B, Mallampalli R, Sun M, Silverstein R, Stolz D, Shapiro S, Ray A, Ray P, Lee J Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection. Mucosal Immunol, 2014-12-10;8(4):896-905. 2014-12-10 [PMID: 25492474] (Mouse)		Mouse
Cao Y, Slaney C, Bidwell B, Parker B, Johnstone C, Rautela J, Eckhardt B, Anderson R BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity. Cancer Res, 2014-09-15;74(18):5091-102. 2014-09-15 [PMID: 25224959] (Mouse)		Mouse
De Filippo K, Neill D, Mathies M, Bangert M, McNeill E, Kadioglu A, Hogg N A new protective role for S100A9 in regulation of neutrophil recruitment during invasive pneumococcal pneumonia. FASEB J, 2014-04-28;28(8):3600-8. 2014-04-28 [PMID: 24776746] (Mouse)		Mouse
Weber S, Wetzel S, Prox J, Lehmann T, Schneppenheim J, Donners M, Saftig P Regulation of adult hematopoiesis by the a disintegrin and metalloproteinase 10 (ADAM10). Biochem Biophys Res Commun, 2013-11-15;442(3):234-41. 2013-11-15 [PMID: 24239882] (Mouse)		Mouse
Bosmann M, Haggadone M, Zetoune F, Sarma J, Ward P The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation. Eur J Immunol, 2013-05-13;43(7):1907-13. 2013-05-13 [PMID: 23575697] (Mouse)		Mouse
von Vietinghoff S, Asagiri M, Azar D Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice. J. Immunol., 2010-06-02;185(1):670-8. 2010-06-02 [PMID: 20519647] (Mouse)		Mouse
von Vietinghoff S, Ley K IL-17A controls IL-17F production and maintains blood neutrophil counts in mice. J. Immunol., 2009-06-19;183(2):865-73. 2009-06-19 [PMID: 19542376] (Mouse)		Mouse
Smith E, Zarbock A, Stark MA, Burcin TL, Bruce AC, Foley P, Ley K IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice. J. Immunol., 2007-12-15;179(12):8274-9. 2007-12-15 [PMID: 18056371] (Mouse)		Mouse
Witowski J, Ksiazek K, Warnecke C, Kuzlan M, Korybalska K, Tayama H, Wisniewska-Elnur J, Pawlaczyk K, Trominska J, Breborowicz A, Jorres A Role of mesothelial cell-derived granulocyte colony-stimulating factor in interleukin-17-induced neutrophil accumulation in the peritoneum. Kidney Int., 2007-01-17;71(6):514-25. 2007-01-17 [PMID: 17228364] (Mouse)		Mouse
Allen GB, Suratt BT, Rinaldi L, Petty JM, Bates JH Choosing the frequency of deep inflation in mice: balancing recruitment against ventilator-induced lung injury. Am. J. Physiol. Lung Cell Mol. Physiol., 2006-05-12;291(4):L710-7. 2006-05-12 [PMID: 16698851] (Mouse)		Mouse
Show All 29 Publications. Collapse Publications.

Array DY414

• G-CSF Antibodies
• G-CSF Antibody Pair
• G-CSF ELISA Kit
• G-CSF Lysates
• G-CSF Proteins
• G-CSF ELISAs
• G-CSF Proteins and Enzymes