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MOS Antibody (S3.1) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity XpSpecies Glossary
Applications WB, IHC, IP
Clone
S3.1
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

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MOS Antibody (S3.1) [Janelia Fluor® 646] Summary

Immunogen
Recombinant (Xenopus laevis) MOS fusion protein
Localization
Cytoplasmic
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
MOS
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for MOS Antibody (S3.1) [Janelia Fluor® 646]

  • c-mos
  • EC 2.7.11
  • EC 2.7.11.1
  • MGC119962
  • MGC119963
  • MSV
  • oncogene MOS, Moloney murine sarcoma virus
  • Oocyte maturation factor mos
  • Proto-oncogene c-Mos
  • proto-oncogene serine/threonine-protein kinase mos
  • v-mos Moloney murine sarcoma viral oncogene homolog

Background

MOS is a 39kDa proto oncogene (c-Mos) encoded protein serine/threonine kinase. MOS is a monomeric protein that indirectly activates MAP kinase (Erk1/2) by directly phosphorylating MAP kinase kinase (Mck, MAPKK, MKK). MOS is known as a cytostatic factor (CSF) and is also thought to arrest unfertilized amphibian and mammalian cells during M phase, thus regulating oocyte maturation. MOS is destroyed before fertilisation, after exit from meiosis II, making it a good marker for studies of eggs during oogenesis and maturation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for MOS Antibody (NB100-2784JF646) (0)

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Secondary Antibodies

 

Isotype Controls

Additional MOS Products

Array NB100-2784JF646

Research Areas for MOS Antibody (NB100-2784JF646)

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol MOS