MMP-9 Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin, and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP-1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by keratinocytes, monocytes, macrophages, and PMN leukocytes. MMP-9 is present in most cases of inflammatory responses. Structurally, MMP-9 may be divided into five distinct domains: a pro-domain which is cleaved upon activation, a gelatin-binding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a proline-rich linker region, and a carboxyl terminal hemopexin-like domain. Compared to the human MMP-9
(Catalog # 911-MP), the mouse enzyme contains extra sequences in the linker region and in the hemopexin-like domain, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 4 confirmed species: Human, Mouse, Complex Species Category, Transgenic Mouse.

We have publications tested in 10 applications: Electron Microscopy, Flow Cytometry, ICC, IHC, IHC-Fr, IHC-P, Immunohistochemistry, Immunoprecipitation, Neutralization, Western Blot.

Showing Publications 1 - 10 of 111. Show All 111 Publications. Collapse Publications.

Publications using AF909	Applications	Species
Wang, D;Saleem, S;Sullivan, RD;Zhao, T;Reed, GL; Differences in Acute Expression of Matrix Metalloproteinases-9, 3, and 2 Related to the Duration of Brain Ischemia and Tissue Plasminogen Activator Treatment in Experimental Stroke International journal of molecular sciences 2024-08-30 [PMID: 39273389] (Immunohistochemistry, Mouse)	Immunohistochemistry	Mouse
Jeong, C;Lee, CH;Lee, Y;Seo, J;Wang, W;Park, KH;Oh, E;Cho, Y;Park, C;Son, YJ;Yoon Park, JH;Kang, H;Lee, KW; Ulmus macrocarpa Hance trunk bark extracts inhibit RANKL-induced osteoclast differentiation and prevent ovariectomy-induced osteoporosis in mice Journal of ethnopharmacology 2023-10-13 [PMID: 37839769] (Western Blot, Mouse)	Western Blot	Mouse
Fu Y, Liu H, Li K et al. C-reactive protein deficiency ameliorates experimental abdominal aortic aneurysms Front Immunol 9/11/2023 [PMID: 37753091]
Fu Y, Liu H, Li K et al. C-reactive protein deficiency ameliorates experimental abdominal aortic aneurysms Front Immunol 2023-09-11 [PMID: 37753091]
Graca, FA;Stephan, A;Minden-Birkenmaier, BA;Shirinifard, A;Wang, YD;Demontis, F;Labelle, M; Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles Nature communications 2023-05-22 [PMID: 37217480] (IHC, Mouse)	IHC	Mouse
Weilai Fu, Haole Liu, Panpan Wei, Congcong Xia, Qingqing Yu, Kangli Tian et al. Genetic deficiency of protein inhibitor of activated STAT3 suppresses experimental abdominal aortic aneurysms Frontiers in Cardiovascular Medicine 3/15/2023 [PMID: 37008329]
A Chakrabort, B Halder, S Mondal, A Barrett, W Zhi, G Csanyi, ME Sabbatini NADPH oxidase 1 in chronic pancreatitis-activated pancreatic stellate cells facilitates the progression of pancreatic cancer American journal of cancer research, 2023-01-15;13(1):118-142. 2023-01-15 [PMID: 36777508] (Western Blot, Complex Species Category)	Western Blot	Complex Species Category
M Crompton, JK Ferguson, R Ramnath, KL Onions, AS Ogier, M Gamez, CJ Down, LJ Skinner, KH Wong, LK Dixon, J Sutak, SJ Harper, P Pontrelli, L Gesualdo, HL Heerspink, RD Toto, GI Welsh, RR Foster, SC Satchell, MJ Butler Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx JCI Insight, 2023-03-08;0(0):. 2023-03-08 [PMID: 36749631] (ICC, Human)	ICC	Human
K Karasaki, H Kokubo, B Bumdelger, N Kaji, C Sakai, M Ishida, M Yoshizumi Angiotensin II Type 1 Receptor Blocker Prevents Abdominal Aortic Aneurysm Progression in Osteoprotegerin-Deficient Mice via Upregulation of Angiotensin (1-7) Journal of the American Heart Association, 2023-01-31;12(3):e027589. 2023-01-31 [PMID: 36718875] (IHC, Mouse, Transgenic Mouse)	IHC	Mouse, Transgenic Mouse
H Shi, Z Yin, Y Koronyo, DT Fuchs, J Sheyn, MR Davis, JW Wilson, MA Margeta, KM Pitts, S Herron, S Ikezu, T Ikezu, SL Graham, VK Gupta, KL Black, M Mirzaei, O Butovsky, M Koronyo-Ha Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia Acta neuropathologica communications, 2022-09-08;10(1):136. 2022-09-08 [PMID: 36076283] (Western Blot, Mouse)	Western Blot	Mouse
T Yamasaki, T Horie, S Koyama, T Nakao, O Baba, M Kimura, N Sowa, K Sakamoto, K Yamazaki, S Obika, Y Kasahara, J Kotera, K Oka, R Fujita, T Sasaki, A Takemiya, K Hasegawa, K Minatoya, T Kimura, K Ono Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways Scientific Reports, 2022-07-14;12(1):11984. 2022-07-14 [PMID: 35835906] (IHC, Mouse)	IHC	Mouse
Liu H, Tian K, Xia C et al. Kunming mouse strain is less susceptible to elastase induced abdominal aortic aneurysms Animal Model Exp Med 3/1/2022 [PMID: 35229996]
S Murthy, S Baruah, JL Bowen, K Keck, BA Wagner, GR Buettner, DB Sykes, J Klesney-Ta TREM-1 is required for enhanced OpZ-induced superoxide generation following priming Journal of leukocyte biology, 2022-01-24;0(0):. 2022-01-24 [PMID: 35075692] (Western Blot, Mouse)	Western Blot	Mouse
K Tian, C Xia, H Liu, B Xu, P Wei, W Fu, M Lu, Y Li, Y Li, D Cheng, E Liu, S Zhao Temporal and Quantitative Analysis of Aortic Immunopathologies in Elastase-Induced Mouse Abdominal Aortic Aneurysms Journal of Immunology Research, 2021-11-16;2021(0):6297332. 2021-11-16 [PMID: 34825008] (IHC, Mouse)	IHC	Mouse
Gui-Li Yang, Shizhao Wang, Shu Zhang, Ye Liu, Xiao Liu, Dong Wang et al. A Protective Role of Tumor Necrosis Factor Superfamily-15 in Intracerebral Hemorrhage-Induced Secondary Brain Injury ASN Neuro 10/1/2021 [PMID: 34596444]
Daniela Fraccarollo, Jonas Neuser, Julian Möller, Christian Riehle, Paolo Galuppo, Johann Bauersachs Expansion of CD10neg neutrophils and CD14+HLA-DRneg/low monocytes driving proinflammatory responses in patients with acute myocardial infarction eLife 7/22/2021 [PMID: 34289931]
S Baik, J Lee, EJ Jeon, BY Park, DW Kim, JH Song, HJ Lee, SY Han, SW Cho, C Pang Diving beetle-like miniaturized plungers with reversible, rapid biofluid capturing for machine learning-based care of skin disease Science Advances, 2021-06-16;7(25):. 2021-06-16 [PMID: 34134988] (IHC, Mouse)	IHC	Mouse
T Hasegawa, V Venkata Su, Y Yahata, M Nakano, S Suzuki, S Suzuki, S Yamada, H Kitaura, I Mizoguchi, Y Noiri, K Handa, M Saito Inhibition of the CXCL9-CXCR3 axis suppresses the progression of experimental apical periodontitis by blocking macrophage migration and activation Scientific Reports, 2021-01-28;11(1):2613. 2021-01-28 [PMID: 33510341] (IHC, Mouse)	IHC	Mouse
M Gantov, P Pagnotta, C Lotufo, GM Rindone, MF Riera, JC Calvo, J Toneatto Beige adipocytes contribute to breast cancer progression Oncology reports, 2020-10-27;45(1):317-328. 2020-10-27 [PMID: 33416183] (Western Blot, Mouse)	Western Blot	Mouse
DG Campelj, CA Timpani, AC Petersen, A Hayes, CA Goodman, E Rybalka The Paradoxical Effect of PARP Inhibitor BGP-15 on Irinotecan-Induced Cachexia and Skeletal Muscle Dysfunction Cancers, 2020-12-17;12(12):. 2020-12-17 [PMID: 33348673] (Western Blot, Mouse)	Western Blot	Mouse
Kui Li, Zheng Zhou, Ju Li, Rui Xiang miR-146b Functions as an Oncogene in Oral Squamous Cell Carcinoma by Targeting HBP1 Technol Cancer Res Treat 12/17/2020 [PMID: 33327874]
W Zhang, W Cheng, R Parlato, X Guo, X Cui, C Dai, L Xu, J Zhu, M Zhu, K Luo, W Zhang, B Dong, J Wang, F Jiang Nucleolar stress induces a senescence-like phenotype in smooth muscle cells and promotes development of vascular degeneration Aging (Albany NY), 2020-11-04;12(21):22174-22198. 11/4/2020 [PMID: 33146634]
Huan Yang, Ting Zhou, Christine M. Sorenson, Nader Sheibani, Bo Liu Myeloid-Derived TSP1 (Thrombospondin-1) Contributes to Abdominal Aortic Aneurysm Through Suppressing Tissue Inhibitor of Metalloproteinases-1 Arteriosclerosis, Thrombosis, and Vascular Biology 12/1/2020 [PMID: 33028100]
Q Zheng, X Dai, W Fang, Y Zheng, J Zhang, Y Liu, D Gu Overexpression of microRNA-367 inhibits angiogenesis in ovarian cancer by downregulating the expression of LPA1 Cancer Cell Int, 2020-10-02;20(0):476. 2020-10-02 [PMID: 33024414] (Western Blot, Human)	Western Blot	Human
SJ Jeong, MJ Cho, NY Ko, S Kim, IH Jung, JK Min, SH Lee, JG Park, GT Oh Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm Exp. Mol. Med., 2020-09-14;0(0):. 2020-09-14 [PMID: 32929220] (Western Blot, Mouse)	Western Blot	Mouse
CY Lu, SC Lai, HH Lee, HT Chien, KP Lan, KM Chen Matrix metalloproteinases activation in Toxocara canis induced pulmonary pathogenesis J Microbiol Immunol Infect, 2020-08-11;0(0):. 2020-08-11 [PMID: 32826193] (IHC, Mouse)	IHC	Mouse
K Yoshimura, H Aoki, C Teruyama, M Iijima, H Tsutsumi, S Kuroda, K Hamano A Novel Hybrid Drug Delivery System for Treatment of Aortic Aneurysms Int J Mol Sci, 2020-08-02;21(15):. 2020-08-02 [PMID: 32748844] (Western Blot, Mouse)	Western Blot	Mouse
T Osthues, B Zimmer, V Rimola, K Klann, K Schilling, P Mathoor, C Angioni, A Weigert, G Geisslinge, C Münch, K Scholich, M Sisignano The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain Cells, 2020-07-21;9(7):. 2020-07-21 [PMID: 32708184] (Neutralization, Mouse)	Neutralization	Mouse
X Gou, Y Xue, H Zheng, G Yang, S Chen, Z Chen, G Yuan Gelatinases Cleave Dentin Sialoprotein Intracellularly Front Physiol, 2020-06-25;11(0):686. 2020-06-25 [PMID: 32670089] (ICC, Mouse)	ICC	Mouse
L Hui, Y Nie, S Li, M Guo, W Yang, R Huang, J Chen, Y Liu, X Lu, Z Chen, Q Yang, Y Wu Matrix metalloproteinase 9 facilitates Zika virus invasion of the testis by modulating the integrity of the blood-testis barrier. PLoS Pathog, 2020-04-17;16(4):e1008509. 2020-04-17 [PMID: 32302362] (IHC, Immunoprecipitation, Western Blot, Mouse, Transgenic Mouse)	IHC, Immunoprecipitation, Western Blot	Mouse, Transgenic Mouse
K Miteva, D Baptista, F Montecucco, M Asrih, F Burger, A Roth, RA Fraga-Silv, N Stergiopul, F Mach, KJ Brandt Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression Sci Rep, 2020-04-01;10(1):5791. 2020-04-01 [PMID: 32238841] (IHC, Mouse)	IHC	Mouse
Amanda R. Kaminski, Edwin T. Moore, Michael J. Daseke, Fritz M. Valerio, Elizabeth R. Flynn, Merry L. Lindsey The compendium of matrix metalloproteinase expression in the left ventricle of mice following myocardial infarction American Journal of Physiology-Heart and Circulatory Physiology 3/1/2020 [PMID: 32083973]
Songlin Li, Eric Y. Hayden, Veronica J. Garcia, Dieu-Trang Fuchs, Julia Sheyn, David A. Daley et al. Activated Bone Marrow-Derived Macrophages Eradicate Alzheimer's-Related A beta 42 Oligomers and Protect Synapses Frontiers in Immunology 1/31/2020 [PMID: 32082319]
K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice Dis Model Mech, 2019-11-12;0(0):. 2019-11-12 [PMID: 31562139] (Western Blot, Mouse)	Western Blot	Mouse
H Zhang, M Liao, M Cao, Z Qiu, X Yan, Y Zhou, H Wu, Y Wang, J Zheng, J Ding, M Wang, Y Liao, X Chen ATRQ β-001 Vaccine Prevents Experimental Abdominal Aortic Aneurysms J Am Heart Assoc, 2019-09-12;8(18):e012341. 2019-09-12 [PMID: 31512549] (IHC-P, Mouse)	IHC-P	Mouse
Wei Wang, Yuan Gao, Hongrui Liu, Wei Feng, Xiaoyan Li, Jie Guo et al. Eldecalcitol, an active vitamin D analog, effectively prevents cyclophosphamide‑induced osteoporosis in rats Experimental and Therapeutic Medicine 7/9/2019 [PMID: 31410111]
Violeta Durán-Laforet, David Fernández-López, Alicia García-Culebras, Juan González-Hijón, Ana Moraga, Sara Palma-Tortosa et al. Delayed Effects of Acute Reperfusion on Vascular Remodeling and Late-Phase Functional Recovery After Stroke Frontiers in Neuroscience 7/23/2019 [PMID: 31396042]
Y Liu, Y Zhang, M Hu, YH Li, XH Cao Carnosic acid alleviates brain injury through NF?κB?regulated inflammation and Caspase?3?associated apoptosis in high fat?induced mouse models Mol Med Rep, 2019-05-27;20(1):495-504. 2019-05-27 [PMID: 31180544] (Western Blot, Mouse)	Western Blot	Mouse
Nagahiro Ochiai, Yutaka Nakachi, Tomotaka Yokoo, Takahiro Ichihara, Tore Eriksson, Yuki Yonemoto et al. Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment Communications Biology 3/1/2019 [PMID: 30854478]
Maulin M. Patel, Amanda R. Behar, Robert Silasi, Girija Regmi, Christopher L. Sansam, Ravi S. Keshari et al. Role of ADTRP (Androgen‐Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function Journal of the American Heart Association 12/21/2018 [PMID: 30571485]
Hiroyuki Kato, Sergio Duarte, Mary G. Miller, Ronald W. Busuttil, Ana J. Coito Overproduction of Tenascin‐C Driven by Lipid Accumulation in the Liver Aggravates Hepatic Ischemia/Reperfusion Injury in Steatotic Mice Liver Transplantation 2/1/2019 [PMID: 30358115]
KM Kniewallne, BM Foidl, C Humpel Platelets isolated from an Alzheimer mouse damage healthy cortical vessels and cause inflammation in an organotypic ex vivo brain slice model Sci Rep, 2018-10-19;8(1):15483. 2018-10-19 [PMID: 30341392] (IHC, Mouse)	IHC	Mouse
Yang Dong, Chun‑Rong Guo, Dan Chen, Sheng‑Min Chen, Yinting Peng, Haiyan Song et al. Association between age‑related hearing loss and cognitive decline in C57BL/6J mice Molecular Medicine Reports 6/1/2018 [PMID: 29901198]
T Hara, PT Phuong, D Fukuda, K Yamaguchi, C Murata, S Nishimoto, S Yagi, K Kusunose, H Yamada, T Soeki, T Wakatsuki, I Imoto, M Shimabukur, M Sata Protease-Activated Receptor-2 Plays a Critical Role in Vascular Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice Circulation, 2018-10-16;0(0):. 2018-10-16 [PMID: 29700120] (IHC-Fr, Mouse)	IHC-Fr	Mouse
X Huang, Z Yue, J Wu, J Chen, S Wang, J Wu, L Ren, A Zhang, P Deng, K Wang, C Wu, X Ding, P Ye, J Xia MicroRNA-21 Knockout Exacerbates Angiotensin II-Induced Thoracic Aortic Aneurysm and Dissection in Mice With Abnormal Transforming Growth Factor-?-SMAD3 Signaling Arterioscler. Thromb. Vasc. Biol., 2018-03-08;0(0):. 2018-03-08 [PMID: 29519942] (IHC-P, Mouse)	IHC-P	Mouse
Lai H, Zhao X, Qin Y, Ding Y. FAK-ERK activation in cell/matrix adhesion induced by the loss of apolipoprotein E stimulates the malignant progression of ovarian cancer. J. Exp. Clin. Cancer Res. 2/20/2018 [PMID: 29458390]
LQ Liu, HS Li, SP Nie, MY Shen, JL Hu, MY Xie Tea Polysaccharide Prevents Colitis-Associated Carcinogenesis in Mice by Inhibiting the Proliferation and Invasion of Tumor Cells Int J Mol Sci, 2018-02-08;19(2):. 2018-02-08 [PMID: 29419740] (Western Blot, Mouse)	Western Blot	Mouse
Natalya G. Dulyaninova, Penelope D. Ruiz, Matthew J. Gamble, Jonathan M. Backer, Anne R. Bresnick S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms Molecular Biology of the Cell 3/1/2018 [PMID: 29282275]
J Vandooren, W Swinnen, E Ugarte-Ber, L Boon, D Dorst, E Martens, G Opdenakker Endotoxemia shifts neutrophils with TIMP-free gelatinase B/ MMP-9 from bone marrow to periphery and induces systematic upregulation of TIMP-1 Haematologica, 2017-08-03;0(0):. 2017-08-03 [PMID: 28775117] (IHC-P, Mouse)	IHC-P	Mouse
ND Thiele, JW Wirth, D Steins, AC Koop, H Ittrich, AW Lohse, J Kluwe TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice Sci Rep, 2017-04-06;7(1):714. 2017-04-06 [PMID: 28386095] (Western Blot, Mouse)	Western Blot	Mouse
M Shimoda, H Yoshida, S Mizuno, T Hirozane, K Horiuchi, Y Yoshino, H Hara, Y Kanai, S Inoue, M Ishijima, Y Okada Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization Controls Endochondral Ossification through Hyaluronan Metabolism Am. J. Pathol, 2017-03-08;0(0):. 2017-03-08 [PMID: 28284715] (IHC-P, Mouse)	IHC-P	Mouse
Smooth muscle cell-specific Tgfbr1 deficiency attenuates neointimal hyperplasia but promotes an undesired vascular phenotype for injured arteries Physiol Rep, 2016-12-01;4(23):. 2016-12-01 [PMID: 27923978] (IHC, Mouse)	IHC	Mouse
Tingting Luo Adipocytes enhance expression of osteoclast adhesion-related molecules through the CXCL12/CXCR4 signalling pathway Cell Prolif, 2016-11-21;0(0):. 11/21/2016 [PMID: 27868262]
Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy Sci Rep, 2016-09-14;6(0):33176. 2016-09-14 [PMID: 27624652] (Western Blot, Mouse)	Western Blot	Mouse
Huey Lin, Mia Angeli, Kwang Jin Chung, Chukwuemeka Ejimadu, Angelica Rivera Rosa, Techung Lee sFRP2 activates Wnt/ beta -catenin signaling in cardiac fibroblasts: differential roles in cell growth, energy metabolism, and extracellular matrix remodeling American Journal of Physiology-Cell Physiology 11/1/2016 [PMID: 27605451]
Thymocyte development in the absence of matrix metalloproteinase-9/gelatinase B Sci Rep, 2016-07-19;6(0):29852. 2016-07-19 [PMID: 27432536] (Flow Cytometry, IHC, Mouse)	Flow Cytometry, IHC	Mouse
Di Cui, Houxuan Li, Lang Lei, Changxing Chen, Fuhua Yan Nonsurgical periodontal treatment reduced aortic inflammation in ApoE(-/-) mice with periodontitis SpringerPlus 12/1/2016 [PMID: 27386384]
Kato H, Duarte S, Liu D, Busuttil R, Coito A Matrix Metalloproteinase-2 (MMP-2) Gene Deletion Enhances MMP-9 Activity, Impairs PARP-1 Degradation, and Exacerbates Hepatic Ischemia and Reperfusion Injury in Mice. PLoS ONE, 2015-09-10;10(9):e0137642. 2015-09-10 [PMID: 26355684] (IHC, Mouse)	IHC	Mouse
Yosef Koronyo, Brenda C. Salumbides, Julia Sheyn, Lindsey Pelissier, Songlin Li, Vladimir Ljubimov et al. Therapeutic effects of glatiramer acetate and grafted CD115⁺ monocytes in a mouse model of Alzheimer's disease Brain 8/1/2015 [PMID: 26049087]
Kawasaki H, Kosugi I, Sakao-Suzuki M, Meguro S, Arai Y, Tsutsui Y, Iwashita T Cytomegalovirus initiates infection selectively from high-level beta1 integrin-expressing cells in the brain. Am J Pathol, 2015-03-19;185(5):1304-23. 2015-03-19 [PMID: 25797647] (Western Blot, Mouse)	Western Blot	Mouse
Ueda , Koshiro, Yoshimura , Koichi, Yamashita , Osamu, Harada , Takasuke, Morikage , Noriyasu, Hamano , Kimikazu Possible dual role of decorin in abdominal aortic aneurysm. PLoS ONE, 2015-03-17;10(3):e0120689. 2015-03-17 [PMID: 25781946] (IHC, Mouse)	IHC	Mouse
Tatiana Y. Besschetnova, Takaharu Ichimura, Negin Katebi, Brad St. Croix, Joseph V. Bonventre, Bjorn R. Olsen Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis Matrix Biology 3/1/2015 [PMID: 25572963]
Dohi , Kenji, Kraemer , Brian C, Erickson , Michelle, McMillan , Pamela J, Kovac , Andrej, Flachbartova , Zuzana, Hansen , Kim M, Shah , Gul N, Sheibani , Nader, Salameh , Therese, Banks , William Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury. PLoS ONE, 2014-09-24;9(9):e108034. 2014-09-24 [PMID: 25251220] (Western Blot, Mouse)	Western Blot	Mouse
Park D, Lee J, Park I, Choi D, Lee S, Song S, Hwang Y, Hong K, Nakaoka Y, Makinen T, Kim P, Alitalo K, Hong Y, Koh G Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity. J Clin Invest, 2014-07-25;124(9):3960-74. 2014-07-25 [PMID: 25061877] (IHC, Mouse)	IHC	Mouse
Labelle , Myriam, Begum , Shahinoo, Hynes , Richard Platelets guide the formation of early metastatic niches. Proc Natl Acad Sci U S A, 2014-07-14;111(30):E3053-61. 2014-07-14 [PMID: 25024172] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Touaitahuata H, Cres G, de Rossi S, Vives V, Blangy A The mineral dissolution function of osteoclasts is dispensable for hypertrophic cartilage degradation during long bone development and growth. Dev Biol, 2014-06-30;393(1):57-70. 2014-06-30 [PMID: 24992711] (IHC, Mouse)	IHC	Mouse
Duarte , Sergio, Kato , Hiroyuki, Kuriyama , Naohisa, Suko , Kathryn, Ishikawa , Tomo-O, Busuttil , Ronald W, Herschman , Harvey R, Coito , Ana J Hepatic ischemia and reperfusion injury in the absence of myeloid cell-derived COX-2 in mice. PLoS ONE, 2014-05-12;9(5):e96913. 2014-05-12 [PMID: 24819536] (IHC, Mouse)	IHC	Mouse
Wang J, Eguchi K, Matsumoto S, Fujiu K, Komuro I, Nagai R, Manabe I The omega-3 polyunsaturated fatty acid, eicosapentaenoic acid, attenuates abdominal aortic aneurysm development via suppression of tissue remodeling. PLoS ONE, 2014-05-05;9(5):e96286. 2014-05-05 [PMID: 24798452] (IHC-P, Mouse)	IHC-P	Mouse
Kato H, Kuriyama N, Duarte S, Clavien P, Busuttil R, Coito A MMP-9 deficiency shelters endothelial PECAM-1 expression and enhances regeneration of steatotic livers after ischemia and reperfusion injury. J Hepatol, 2014-01-08;60(5):1032-9. 2014-01-08 [PMID: 24412604] (IHC-P, Mouse)	IHC-P	Mouse
Gonzalez-Quesada C, Cavalera M, Biernacka A, Kong P, Lee D, Saxena A, Frunza O, Dobaczewski M, Shinde A, Frangogiannis N Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation. Circ Res, 2013-09-30;113(12):1331-44. 2013-09-30 [PMID: 24081879] (Western Blot, Mouse)	Western Blot	Mouse
Salmon M, Johnston W, Woo A, Pope N, Su G, Upchurch G, Owens G, Ailawadi G KLF4 regulates abdominal aortic aneurysm morphology and deletion attenuates aneurysm formation. Circulation, 2013-09-10;128(11):S163-74. 2013-09-10 [PMID: 24030402] (IHC-P, Mouse)	IHC-P	Mouse
Jun Watanabe, Ashok K. Shetty, Bharathi Hattiangady, Dong-Ki Kim, Jessica E. Foraker, Hidetaka Nishida et al. Administration of TSG-6 improves memory after traumatic brain injury in mice Neurobiology of Disease 11/1/2013 [PMID: 23851308]
Muruganandan S, Dranse H, Rourke J, McMullen N, Sinal C Chemerin neutralization blocks hematopoietic stem cell osteoclastogenesis. Stem Cells, 2013-10-01;31(10):2172-82. 2013-10-01 [PMID: 23766088] (Western Blot, Mouse)	Western Blot	Mouse
Norifumi Ohashi, Tomohide Hori, Florence Chen, Sura Jermanus, Akimasa Nakao, Shinji Uemoto et al. Matrix metalloproteinase-9 in the initial injury after hepatectomy in mice World Journal of Gastroenterology 5/28/2013 [PMID: 23716982]
Zhou H, Yan H, Cannon J, Springer L, Green J, Pham C CD43-mediated IFN-gamma production by CD8+ T cells promotes abdominal aortic aneurysm in mice. J Immunol, 2013-04-12;190(10):5078-85. 2013-04-12 [PMID: 23585675] (IHC, Mouse)	IHC	Mouse
Immunodominant fragments of myelin basic protein initiate T cell-dependent pain. J Neuroinflammation, 2012-06-07;9(0):119. 2012-06-07 [PMID: 22676642] (IHC, Mouse)	IHC	Mouse
Norifumi Ohashi, Tomohide Hori, Florence Chen, Sura Jermanus, Christopher B Eckman, Akimasa Nakao et al. Matrix metalloproteinase-9 contributes to parenchymal hemorrhage and necrosis in the remnant liver after extended hepatectomy in mice World Journal of Gastroenterology 5/21/2012 [PMID: 22654423]
Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice. J. Biol. Chem., 2012-03-23;287(20):16356-64. 2012-03-23 [PMID: 22447930] (IHC-P, Mouse)	IHC-P	Mouse
Kim Y, Remacle AG, Chernov AV The MMP-9/TIMP-1 axis controls the status of differentiation and function of myelin-forming Schwann cells in nerve regeneration. PLoS ONE, 2012-03-16;7(3):e33664. 2012-03-16 [PMID: 22438979] (ICC, Western Blot, Mouse)	ICC, Western Blot	Mouse
Sergio Duarte, Takashi Hamada, Naohisa Kuriyama, Ronald W. Busuttil, Ana J. Coito TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) DEFICIENCY LEADS TO LETHAL PARTIAL HEPATIC ISCHEMIA AND REPERFUSION INJURY Hepatology 9/1/2012 [PMID: 22407827]
Takuro Hisanaga, Shuji Terai, Takuya Iwamoto, Taro Takami, Naoki Yamamoto, Tomoaki Murata et al. TNFR1-mediated signaling is important to induce the improvement of liver fibrosis by bone marrow cell infusion Cell and Tissue Research 10/11/2011 [PMID: 21987217]
Naohisa Kuriyama, Sergio Duarte, Takashi Hamada, Ronald W. Busuttil, Ana J. Coito Tenascin-C: A novel mediator of hepatic ischemia and reperfusion injury Hepatology 12/1/2011 [PMID: 21898491]
Dahiya S, Givvimani S, Bhatnagar S Osteopontin-Stimulated Expression of Matrix Metalloproteinase-9 Causes Cardiomyopathy in the mdx Model of Duchenne Muscular Dystrophy. J. Immunol., 2011-08-01;187(5):2723-31. 2011-08-01 [PMID: 21810612] (Western Blot, Mouse)	Western Blot	Mouse
Renda L. Hawwa, Michael A. Hokenson, Yulian Wang, Zheping Huang, Surendra Sharma, Juan Sanchez-Esteban Differential Expression of MMP-2 and -9 and their Inhibitors in Fetal Lung Cells Exposed to Mechanical Stretch: Regulation by IL-10 Lung 8/1/2011 [PMID: 21701831]
Meissburger B, Stachorski L, Roder E, Rudofsky G, Wolfrum C Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) controls adipogenesis in obesity in mice and in humans. Diabetologia, 2011-03-25;54(6):1468-79. 2011-03-25 [PMID: 21437772] (Western Blot, Mouse)	Western Blot	Mouse
Martin Roderfeld, Timo Rath, Frank Lammert, Christian Dierkes, Jürgen Graf, Elke Roeb Innovative immunohistochemistry identifies MMP-9 expressing macrophages at the invasive front of murine HCC World Journal of Hepatology 5/27/2010 [PMID: 21160992]
Bhatnagar S, Panguluri SK, Gupta SK, Dahiya S, Lundy RF, Kumar A Tumor necrosis factor-alpha regulates distinct molecular pathways and gene networks in cultured skeletal muscle cells. PLoS ONE, 2010-10-12;5(10):e13262. 2010-10-12 [PMID: 20967264] (Western Blot, Mouse)	Western Blot	Mouse
Xu D, McKee CM, Cao Y Matrix metalloproteinase-9 regulates tumor cell invasion through cleavage of protease nexin-1. Cancer Res., 2010-08-24;70(17):6988-98. 2010-08-24 [PMID: 20736374] (Western Blot, Mouse)	Western Blot	Mouse
Jian Fu, Fang Jin, Jirong Zhang, Kathryn Fong, Daniel E. Bassi, Ricardo Lopez De Cicco et al. VILIP-1 Expression In Vivo Results in Decreased Mouse Skin Keratinocyte Proliferation and Tumor Development PLoS ONE 4/15/2010 [PMID: 20419170]
Ye Y, Pringle LM, Lau AW TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaB. Oncogene, 2010-04-26;29(25):3619-29. 2010-04-26 [PMID: 20418905] (IHC-P, Mouse)	IHC-P	Mouse
Volker Rudolph, René P Andrié, Tanja K Rudolph, Kai Friedrichs, Anna Klinke, Birgit Hirsch-Hoffmann et al. Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation Nature Medicine 4/1/2010 [PMID: 20305660]
John M. Hartney, Jeanette Brown, Hong Wei Chu, Ling Yi Chang, Roberta Pelanda, Raul M. Torres Arhgef1 regulates alpha5beta1 integrin-mediated matrix metalloproteinase expression and is required for homeostatic lung immunity The American Journal of Pathology 3/1/2010 [PMID: 20093499]
Schneider DJ, Lindsay JC, Zhou Y, Molina JG, Blackburn MR Adenosine and osteopontin contribute to the development of chronic obstructive pulmonary disease. FASEB J., 2009-08-31;24(1):70-80. 2009-08-31 [PMID: 19720619] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Page K, Ledford JR, Zhou P, Wills-Karp M A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice. J. Immunol., 2009-08-10;183(5):3400-8. 2009-08-10 [PMID: 19667087] (Western Blot, Mouse)	Western Blot	Mouse
Hamada T, Duarte S, Tsuchihashi S, Busuttil RW, Coito AJ Inducible nitric oxide synthase deficiency impairs matrix metalloproteinase-9 activity and disrupts leukocyte migration in hepatic ischemia/reperfusion injury. Am. J. Pathol., 2009-05-14;174(6):2265-77. 2009-05-14 [PMID: 19443702] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Derouette JP, Wong C, Burnier L, Morel S, Sutter E, Galan K, Brisset AC, Roth I, Chadjichristos CE, Kwak BR Molecular role of Cx37 in advanced atherosclerosis: a micro-array study. Atherosclerosis, 2009-02-27;206(1):69-76. 2009-02-27 [PMID: 19345950] (IHC, Mouse)	IHC	Mouse
Lukkarinen H, Hogmalm A, Lappalainen U, Bry K Matrix metalloproteinase-9 deficiency worsens lung injury in a model of bronchopulmonary dysplasia. Am. J. Respir. Cell Mol. Biol., 2008-12-18;41(1):59-68. 2008-12-18 [PMID: 19097983] (IHC-P, Mouse)	IHC-P	Mouse
De Palma AM, Verbeken E, Van Aelst I, Van den Steen PE, Opdenakker G, Neyts J Increased gelatinase B/matrix metalloproteinase 9 (MMP-9) activity in a murine model of acute coxsackievirus B4-induced pancreatitis. Virology, 2008-10-16;382(1):20-7. 2008-10-16 [PMID: 18929380] (IHC-P, Mouse)	IHC-P	Mouse
Morschl E, Molina JG, Volmer JB, Mohsenin A, Pero RS, Hong JS, Kheradmand F, Lee JJ, Blackburn MR A3 adenosine receptor signaling influences pulmonary inflammation and fibrosis. Am. J. Respir. Cell Mol. Biol., 2008-06-27;39(6):697-705. 2008-06-27 [PMID: 18587054] (IHC-P, Mouse)	IHC-P	Mouse
Crocker SJ, Frausto RF, Whitton JL, Milner R A novel method to establish microglia-free astrocyte cultures: comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia. Glia, 2008-08-15;56(0):1187-98. 2008-08-15 [PMID: 18449943] (ICC, Mouse)	ICC	Mouse
Juncos JP, Tracz MJ, Croatt AJ, Grande JP, Ackerman AW, Katusic ZS, Nath KA Genetic deficiency of heme oxygenase-1 impairs functionality and form of an arteriovenous fistula in the mouse. Kidney Int., 2008-03-26;74(1):47-51. 2008-03-26 [PMID: 18368029] (Western Blot, Mouse)	Western Blot	Mouse
Hamada T, Tsuchihashi S, Avanesyan A, Duarte S, Moore C, Busuttil RW, Coito AJ Cyclooxygenase-2 deficiency enhances Th2 immune responses and impairs neutrophil recruitment in hepatic ischemia/reperfusion injury. J. Immunol., 2008-02-01;180(3):1843-53. 2008-02-01 [PMID: 18209082] (IHC-Fr, Western Blot, Mouse)	IHC-Fr, Western Blot	Mouse
Perri SR, Annabi B, Galipeau J Angiostatin inhibits monocyte/macrophage migration via disruption of actin cytoskeleton. FASEB J., 2007-07-10;21(14):3928-36. 2007-07-10 [PMID: 17622568] (Western Blot, Mouse)	Western Blot	Mouse
Zozulya AL, Reinke E, Baiu DC, Karman J, Sandor M, Fabry Z Dendritic cell transmigration through brain microvessel endothelium is regulated by MIP-1alpha chemokine and matrix metalloproteinases. J. Immunol., 2007-01-01;178(1):520-9. 2007-01-01 [PMID: 17182592] (ICC, Mouse)	ICC	Mouse
Ivanov S, Bozinovski S, Bossios A, Valadi H, Vlahos R, Malmhall C, Sjostrand M, Kolls JK, Anderson GP, Linden A Functional relevance of the IL-23-IL-17 axis in lungs in vivo. Am. J. Respir. Cell Mol. Biol., 2006-12-01;36(4):442-51. 2006-12-01 [PMID: 17142310] (ICC, Mouse)	ICC	Mouse
Rafei M, Wu JH, Annabi B, Lejeune L, Francois M, Galipeau J A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex. Blood, 2006-11-02;109(5):2234-42. 2006-11-02 [PMID: 17082320] (Western Blot, Mouse)	Western Blot	Mouse
Ogier C, Bernard A, Chollet AM, LE Diguardher T, Hanessian S, Charton G, Khrestchatisky M, Rivera S Matrix metalloproteinase-2 (MMP-2) regulates astrocyte motility in connection with the actin cytoskeleton and integrins. Glia, 2006-09-01;54(4):272-84. 2006-09-01 [PMID: 16845676] (ICC, Mouse)	ICC	Mouse
Ramsey KH, Sigar IM, Schripsema JH, Shaba N, Cohoon KP Expression of matrix metalloproteinases subsequent to urogenital Chlamydia muridarum infection of mice. Infect. Immun., 2005-10-01;73(10):6962-73. 2005-10-01 [PMID: 16177376] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Sergejeva S, Ivanov S, Lotvall J, Linden A Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation. Am. J. Respir. Cell Mol. Biol., 2005-05-18;33(3):248-53. 2005-05-18 [PMID: 15901616] (ICC, Mouse)	ICC	Mouse
Chen KM, Lee HH, Chou HL, Liu JY, Tsai BC, Lai SC Upregulation of MMP-9/TIMP-1 enzymatic system in eosinophilic meningitis caused by Angiostrongylus cantonensis. Int J Exp Pathol, 2005-04-01;86(2):81-9. 2005-04-01 [PMID: 15810979] (IHC-P, Western Blot, Mouse)	IHC-P, Western Blot	Mouse
Tseng YK, Tu WC, Lee HH, Chen KM, Chou HL, Lai SC Ultrastructural localization of matrix metalloproteinase-9 in eosinophils from the cerebrospinal fluid of mice with eosinophilic meningitis caused by Angiostrongylus cantonensis. Ann Trop Med Parasitol, 2004-12-01;98(8):831-41. 2004-12-01 [PMID: 15667715] (Electron Microscopy, Western Blot, Mouse)	Electron Microscopy, Western Blot	Mouse
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Images	Ratings	Applications	Species	Date	Details
	4 reviewed by: Verified Customer	WB	Mouse	01/12/2015	View Summary Application Western Blot Sample Tested See PMID 23766088 Species Mouse
	4 reviewed by: Verified Customer	IHC-Fr	Mouse	01/12/2015	View Summary Application Immunohistochemistry-Frozen Sample Tested See PMID 23060524 Species Mouse

Array AF909

• MMP-9 Antibodies
• MMP-9 Antibody Pairs
• MMP-9 ELISA Kits
• MMP-9 Lysate
• MMP-9 Proteins
• MMP-9 ELISAs
• MMP-9 Proteins and Enzymes